in the present study the effect of the locally produced genetic adjuvant of ginea pig specific cpg-motif-containing oligodeoxynucleotide (cpg-odn) in an inactivated fmd virus vaccine was evaluated. boosting the ginea pigs with fmd vaccine along with cpg-odn adjuvant produced relatively higher ratio (5-fold) of fmdv-specific igg2a / igg1 than those vaccinated in the absence of cpg-odn. the neutr...

In the present study the effect of the locally produced genetic adjuvant of ginea pig specific CpG-motif-containing oligodeoxynucleotide (CpG-ODN) in an inactivated FMD virus vaccine was evaluated. Boosting the ginea pigs with FMD vaccine along with CpG-ODN adjuvant produced relatively higher ratio (5-fold) of FMDV-specific IgG2a / IgG1 than those vaccinated in the absence of CpG-ODN. The neutr...

introduction: in this study, we evaluated the activity of garlic extract against dermatophytes which is planned to be used instead of chemical durgs. garlic has been widely used as medicine since ancient times for varieties of illnesses, including abdominal pain, parasitic infection, insect and snakebites, hemorrhoid and rheumatism. in the last decades, garlic has been reported to display antib...

Background: Species identification in commercially processed food and feed products is one of the important issues. This study was conducted to develop a genetic method for the detection of pig and cattle species in processed food and feed products using newly designed species-specific primers targeting mitochondrial 12S rRNA gene fragments. Methods: Two sets of specific primers were designed ...

The enterotoxins (ETs) of Clostridium perfringens isolated from enterotoxemic or diarrheic alpacas, pigs, calves, dogs, and horses were obtained from sporulated cell extracts. The ETs from alpaca, pig, and calf isolates were chromatographed on Sephadex G-lOO. Monoclonal antibodies (MAbs) against ETs derived from alpaca, pig, and calf C. perfringens isolates were produced. The MAbs were used...

      Flavonoids could serve as potent inhibitors of xanthine oxidase (XO). In the present study, the effects of Ruta graveolens L. extract and its major isolated flavonoids, quercetin and rutin, on guinea pig liver XO have been investigated. The inhibitory effects of R. graveolens, quercetin and its glycoside form, rutin, were assayed spectrophotometrically. R. graveolens...

Chromosomal patterns of experimental animals are useful tools for cytogenetics research and animal breeding. Chromosome investigations of the hairless guinea pig are rare, therefore, karyotype of hairless guinea pigs (twelve male and female) was studied using metaphase spreads of bone marrows and G banding techniques. The chromosomes diploid number was 2n= 64 and polymorphism of three type chro...

there is documented evidence that infection in laboratory animals can often influence the outcome of experiments. all infections, apparent or inapparent, are likely to increase biological variability. as a research project concerning the diversity and distribution of parasites of rabbit and guinea pig in a conventional laboratory animal house, about 87 rabbits (from 700 ) and 105 guinea pigs (f...