giant cell glioblastoma is an extremely rare variant of glioblastoma (who grade iv) which is characterized by a predominance of bizarre, multinucleated giant cells. these tumors comprise of 0.8% of brain tumors and up to 5% of glioblastomas. in pediatric age group, these tumors are still uncommon with only around 53 published cases since 1952. here, we report a case of a 12-year old female pati...

giant cell tumors (gct) are benign tumors with potential for aggressive behavior and capacity to metastasize. although rarely lethal, benign bone tumors may be associated with a substantial disturbance of the local bony architecture that can be particularly troublesome in peri-articular locations. its histogenesis remains unclear. it is characterized by a proliferation of mononuclear stromal ce...

background and aims. the correlation between morphology of giant cells in peripheral granulomas of the jaws and the aggressive behavior of the lesion is unknown. this study investigated the correlation between the histopathologic features with demographic, gross and radiographic findings in giant cell granulomas. materials and methods. in this analytical study, data from 23 cases of central gia...

giant cell carcinoma of the endometrium is a rare and an aggressive tumor that should be distinguished from other endometrial tumors with a prominent giant cell component, including trophoblastic tumors, certain primary sarcomas, and malignant mixed müllerian tumors. at present, cumulative data on this rare histological variant is limited and the prognostic significance of the presence and the ...

objective: the purpose of this study was to retrospectively analyze the demographic characteristics of patients with central giant cell granulomas (cgcgs) and peripheral giant cell granulomas (pgcgs) in an iranian population. methods: in this 38-year retrospective study, the data were obtained from records of 1019 patients with cgcg and pgcg of the jaws referred to the department of oral and ma...

giant cell fibroma (gcf) was described as a new entity of fibrous hyperplastic soft tissue. it seems that stimulus from an unexplained origin can have a role in its etiology. histopathologically gcf is consisted of multinucleated fibroblasts that have oval shape nuclei within the eosinophilic cytoplasm. surgical excision is the treatment of choice and recurrence is very rare. here we report a c...

background: giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull. giant cell tumor (gct) of the sphenoid bone is relatively rare. in this report, we describe a tumor of the greater wing of left sphenoid bone. case presentation: a 31-year-old female was presented with headache, proptosis and diplopia of her left eye. cranial magnetic resonance ima...

Giant cell carcinoma of the endometrium is a rare and an aggressive tumor that should be distinguished from other endometrial tumors with a prominent giant cell component, including trophoblastic tumors, certain primary sarcomas, and malignant mixed müllerian tumors. At present, cumulative data on this rare histological variant is limited and the prognostic significance of the presence and the ...

BACKGROUND AND AIM: Giant cell lesions as a group of the oral and maxillofacial lesions are common and potentially destructive. The aim of this study was to assess the frequency of oral lesions containing giant cells in a 22-year period in Isfahan Dental School, Iran.METHODS: In this epidemiological, cross-sectional, retrospective study the archive information in the Department of Oral Patholog...