نتایج جستجو برای: germ cell transplantation

تعداد نتایج: 1782456  

Journal: :journal of reproduction and infertility 0

some cases of male infertility are due to the destructive side-effects of anticancer treatment methods such as chemo and radiotherapies on germ cell lines. the increase in the survival rate of cancer patients who undergo treatment, especially children, has drawn attention to fertility preservation. the most common and effective technique in preserving male fertility is sperm freezing and its su...

Journal: :avicenna journal of medical biotechnology 0

spermatogonia are the male germ line stem cells whose life long expansion is needed for permanent production of spermatozoa. the present study was designed to examine the effect of hcg treatment on germ cell proliferation following stem cell transplantation in mice. spermatogonial stem cells were isolated from neonatal mice testes and characterized by alkaline phosphatase, immunoreactivity and ...

Journal: :international journal of reproductive biomedicine 0
mohammad mehdi akhondi arash mohazzab mahmood jeddi-tehrani mohammad reza sadeghi akram eidi abbas khodadadi

background: spermatogonial stem cells (sscs), a subset of undifferentiated type a spermatogonia, are the foundation of complex process of spermatogenesis and could be propagated in vitro culture conditions for long time for germ cell transplantation and fertility preservation. objective: the aim of this study was in vitro propagation of human spermatogonial stem cells (sscs) and improvement of ...

Journal: :cell journal 0

objective: testicular cell transplantation has been widely used to investigate the restoration of fertility in rodent models. in this research we apply transplantation as a treatment method in the cryptorchid model and compare this method with orchidopexy, which is the routine treatment for this problem. we studied the controversial effects of treatment on the number of germ cells and other mor...

Journal: :مجله دانشکده پزشکی دانشگاه علوم پزشکی تهران 0
اسدالله سلیمی salimi a سیدمرتضی سجادی sajjadi sm پیمان حداد haddat p

testicular germ-cell tumors are the most common malignancy among men aged 20-40 years, and 60 percent of them are seminomas. these tumors are now an important socio-economic problem, considering their growing incidence. thus we undertook to evaluate the results of curative irradiation in our testicular seminoma patients and compare them to literature results considering the use of cobalt-60 sys...

2004
Marjut Otala Leo Dunkel Olli Ritvos Oskari Heikinheimo Outi Hovatta

................................................................................................................................. 8 INTRODUCTION....................................................................................................................... 10 REVIEW OF LITERATURE..................................................................................................... 13 APOPT...

Journal: :cell journal 0

introduction: transplantation of germ cells restores the male fertility. nevertheless, a lot of questions remain incompletely resolved. the aim of this study was to evaluate in vitro colonization efficiency of germ cells and sperm production capacity of spermatogonial cells before and after culture by sperm number assay in epididymis of recipient mice. materials and methods: we developed a sert...

Journal: :Human reproduction update 2003
N Sofikitis A Kaponis Y Mio D Makredimas D Giannakis Y Yamamoto N Kanakas H Kawamura J Georgiou M Schrader E Lolis X Giannakopoulos D Loutradis V Tarlatzis I Miyagawa

Results from the transplantation of donor male germ cells into xenogeneic recipient seminiferous tubules indicate that donor spermatogonia are capable of differentiating to form spermatozoa morphologically characteristic of the donor species. Germ cell transplantation procedures combined with developments in freezing, culturing or enriching germ cell populations have applications of paramount i...

2006
I. Dobrinski

It was first reported in 1994, that transplantation of germ cells from fertile donor mice to the testes of infertile recipient mice can result in donorderived spermatogenesis and transmission of the donor haplotype to offspring of recipient animals. More recently, germ cell transplantation was successfully performed also in large animals. Importantly, germ cell transplantation was successful be...

Journal: :Biology of Reproduction 2002

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