نتایج جستجو برای: genomic targeted therapy

تعداد نتایج: 883589  

Journal: :gene, cell and tissue 0
janella hudson department of health outcomes and behavior, h. lee moffitt cancer center and research institute, tampa, united states teresita munoz-antonia department of tumor biology, h. lee moffitt cancer center and research institute, tampa, united states eric haura department of thoracic oncology, h. lee moffitt cancer center and research institute, tampa, united states; department of oncologic science, morsani college of medicine, university of south florida, tampa, united states doug cress department of molecular oncology, h. lee moffitt cancer center and research institute, tampa, united states vani n. simmons department of health outcomes and behavior, h. lee moffitt cancer center and research institute, tampa, united states; department of oncologic science, morsani college of medicine, university of south florida, tampa, united states gwendolyn p. quinn department of health outcomes and behavior, h. lee moffitt cancer center and research institute, tampa, united states; department of oncologic science, morsani college of medicine, university of south florida, tampa, united states; department of health outcomes and behavior, h. lee moffitt cancer center and research institute, tampa, united states. tel: +1-8137451359

Journal: :iranian journal of nuclear medicine 2009
mohamadreza nouri mahdavi

neuroendocrine tumors (nets) constitute a heterogeneous group of neoplasms including carcinoids, pancreatic neuroendocrine tumors, pituitary tumors, medullary thyroid carcinoma and phaeochromocytomas. the symptoms and the outcome of nets differ considerably between patients depending on several factors. by labelling tracers with a radioisotope, the tracer acts as a carrier to deliver the radioa...

Journal: :razavi international journal of medicine 0
narges jafarzadeh department of research and education, razavi hospital, mashhad, ir iran hami ashraf department of research and education, razavi hospital, mashhad, ir iran; zakaria idea and innovation support and leading center, tehran, ir iran fahimeh khoshroo department of research and education, razavi hospital, mashhad, ir iran alireza sepehri shamloo student research committee, mashhad university of medical sciences, mashhad, ir iran farzad bidouei department of research and education, razavi hospital, mashhad, ir iran kamran ghaffarzadehgan department of research and education, razavi hospital, mashhad, ir iran; department of research and education, razavi hospital, mashhad, ir iran. tel: +98-5116004594, fax: +98-5116668883

context triple negative breast cancer (tnbc) is a heterogeneous group of diseases that is negative for esterogen receptor (er) progesteron receptor (pr) and human epidermal growth factor receptor 2 (her2). this type of breast cancer is typically high-grade carcinomas, although low-grade tumors occur. the aim of this review is to focus on molecular classification and features, prognostic markers...

Journal: :modares journal of medical sciences: pathobiology 2015
saeedeh ghiasvand fatemeh rahbarizadeh majid sadeghizadeh

background: prostate cancer after lung cancer is the second cause of cancer-associated death in men. in recent years, targeted therapy of cancer has attracted researchers attention. the targeted therapy lead to decrease in side effects of drugs. studies have indicated that targeting peptides for cancer cells represent valuable tools for diagnostic and therapeutic. recently, phage display peptid...

Journal: :iranian journal of public health 0
mohammad amir mishan asieh heirani-tabasi neda mokhberian malihe hassanzade hamid kalalian moghaddam ahmad reza bah­rami

background: chemokine receptors have been shown to play an important role in the development and metastatic spread of various malignancies. in this study, the gene expression profile of some key chemokine receptors involved in metastasis has been investigated in esophageal and breast cancer cell lines.   methods: in a descriptive study, gene expression profile of ccr1, ccr6, ccr7, ccr9, cxcr1, ...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2014
Helen Rizos Alexander M Menzies Gulietta M Pupo Matteo S Carlino Carina Fung Jessica Hyman Lauren E Haydu Branka Mijatov Therese M Becker Suzanah C Boyd Julie Howle Robyn Saw John F Thompson Richard F Kefford Richard A Scolyer Georgina V Long

PURPOSE Multiple BRAF inhibitor resistance mechanisms have been described, however, their relative frequency, clinical correlates, and effect on subsequent therapy have not been assessed in patients with metastatic melanoma. EXPERIMENTAL DESIGN Fifty-nine BRAF(V600)-mutant melanoma metastases from patients treated with dabrafenib or vemurafenib were analyzed. The genetic profile of resistance...

2015
David Deng Biaoru Li

Some diseases including tumor, genetic diseases and uncured diseases in nerve, endocrine, cardiovascular systems require physicians to address a question about effective prevention and treatment[1]. This is why physicians should apply for new techniques available as soon as possible. Now some important discoveries in enhancing the therapeutic effect have emerged in clinical fields such as “pers...

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