نتایج جستجو برای: genomic targeted therapy
تعداد نتایج: 883589 فیلتر نتایج به سال:
neuroendocrine tumors (nets) constitute a heterogeneous group of neoplasms including carcinoids, pancreatic neuroendocrine tumors, pituitary tumors, medullary thyroid carcinoma and phaeochromocytomas. the symptoms and the outcome of nets differ considerably between patients depending on several factors. by labelling tracers with a radioisotope, the tracer acts as a carrier to deliver the radioa...
context triple negative breast cancer (tnbc) is a heterogeneous group of diseases that is negative for esterogen receptor (er) progesteron receptor (pr) and human epidermal growth factor receptor 2 (her2). this type of breast cancer is typically high-grade carcinomas, although low-grade tumors occur. the aim of this review is to focus on molecular classification and features, prognostic markers...
background: prostate cancer after lung cancer is the second cause of cancer-associated death in men. in recent years, targeted therapy of cancer has attracted researchers attention. the targeted therapy lead to decrease in side effects of drugs. studies have indicated that targeting peptides for cancer cells represent valuable tools for diagnostic and therapeutic. recently, phage display peptid...
background: chemokine receptors have been shown to play an important role in the development and metastatic spread of various malignancies. in this study, the gene expression profile of some key chemokine receptors involved in metastasis has been investigated in esophageal and breast cancer cell lines. methods: in a descriptive study, gene expression profile of ccr1, ccr6, ccr7, ccr9, cxcr1, ...
PURPOSE Multiple BRAF inhibitor resistance mechanisms have been described, however, their relative frequency, clinical correlates, and effect on subsequent therapy have not been assessed in patients with metastatic melanoma. EXPERIMENTAL DESIGN Fifty-nine BRAF(V600)-mutant melanoma metastases from patients treated with dabrafenib or vemurafenib were analyzed. The genetic profile of resistance...
Some diseases including tumor, genetic diseases and uncured diseases in nerve, endocrine, cardiovascular systems require physicians to address a question about effective prevention and treatment[1]. This is why physicians should apply for new techniques available as soon as possible. Now some important discoveries in enhancing the therapeutic effect have emerged in clinical fields such as “pers...
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