background in spite of dozens of clinical trials to establish effective therapeutic and/or preventive vaccine to resolve hcv infection, no real vaccine has been proved to date. genetic vaccines based on replication-defective adenoviruses have proved to elicit strong and long lasting t-cell responses against a number of viral antigens and are even currently being used for vaccine trials in human...

In this work, a Genetic Algorithm boosted Least Square Support Vector Machine model by a set of linear equations instead of a quadratic program, which is improved version of Support Vector Machine model, was used for estimation of 98 pure compounds second virial coefficient. Compounds were classified to the different groups. Finest parameters were obtained by Genetic Algorithm method ...

support vector machine (svm) was used to analyze the occurrence of roach in flemish stream basins (belgium). several habitat and physico?chemical variables were used as inputs for the model development. the biotic variable merely consisted of abundance data which was used for predicting presence/absence of roach. genetic algorithm (ga) was combined with svm in order to select the most important...

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different approaches have been proposed for feature selection to obtain suitable features subset among all features. these methods search feature space for feature subsets which satisfies some criteria or optimizes several objective functions. the objective functions are divided into two main groups: filter and wrapper methods.  in filter methods, features subsets are selected due to some measu...

a robust and reliable quantitative structure-property relationship (qspr) study was established to forecast the melting points (mps)  of a diverse and long set including 250 drug-like compounds. based on the calculated descriptors by dragon software package, to detect homogeneities and to split the whole dataset into training and test sets, a principal component analysis (pca) approach was used...

in this paper, first, an initial feature vector for vocal fold pathology diagnosis is proposed. then, for optimizing the initial feature vector, a genetic algorithm is proposed. some experiments are carried out for evaluating and comparing the classification accuracies which are obtained by the use of the different classifiers (ensemble of decision tree, discriminant analysis and k-nearest neig...