background and objectives: bacillus anthracis is one of the most homogenous bacteria ever described. bacillus anthracis 17jb is a laboratory strain. it is broadly used as a challenge strain in guinea pigs for potency test of anthrax vaccine. material and methods: this work describes genetic characterization of b. anthracis 17 jb strain using the snps and mlva genotyping. results and conclusion:...

clostridium perfringens is an important pathogen that provokes numerous different diseases. this bacterium is classified into five various types, each of which capable of causing a distinct disease. there are various methods for the bacterial identification, many are labor-intensive, time-consuming, expensive and also show low sensitivity and specificity. the aim of this research was to identif...

Until the advent of preimplantation genetic diagnosis (PGD) in the 90’s of the last century, the only efficient means to find out whether an offspring has inherited a genetic disease from a couple who are carriers of the defective gene is through prenatal diagnosis (PND). However, if the fetus is found to have the genetic disease, presently the only available treatment is to abort the fetus, an...

Background and Purpose: Candida albicans is the most prevalent Candida species isolated from animals. Candidiasis can be systemic in animals or may affect a single organ, such as the mouth, urinary tract, and skin. The aim of the present study was to determine the genetic diversity of C. albicans isolated from different animals and investigate the presence of a relationship between host specifi...

A civil paternity investigation involving the parents of deceased alleged father in order to establish a family relationship is presented. On basis 23 autosomal short tandem repeat (aSTR) genotyping results, conclusive proof was not achieved, as probability (W) calculated 0.99988. Additional genetic data 17 classical and non-classical human leukocyte alleles (HLA) typing by next-generation sequ...

background and objective: shigella species belong to the family enterobacteriaceae, which cause dysentery with abdominal pain and tenesmus in human. our country is one of the endemic and occasional epidemic areas of the disease. in the present study, repetitive extragenic palindromic polymerase chain reaction (rep-pcr) technique that has high differentiation and specificity power compared to ph...

Strain typing of microbial pathogens has two major aims: (i). to index genetic microvariation for use in outbreak investigations and (ii). to index genetic macrovariation for use in phylogenetic and population-based analyses. Until now, there has been no clear indication that one genetic marker can efficiently be used for both purposes. Previously, we had shown that DNA sequence analysis of the...