objectives: the aim of this randomized clinical trial was to assess the efficacy of stimdate compared to ritalin in the treatment of children with attention deficit hyperactivity disorder (adhd). method: sixty four subjects (45 boys and 15 girls) aged 5-13 who were diagnosed with adhd based on (dsm-iv-tr) criteria were selected for this study. the subjects were randomly assigned to two groups: ...

Shortages of prescription generic drugs have recently made headlines in Canada and elsewhere. The causes and possible solutions for these shortages are still unclear. With the failure of "market forces," has the time come to establish a Crown corporation to ensure the supply of essential drugs?

We develop a new model that simultaneously captures two principal sources of heterogeneity: variation across segments of consumers and variation across clusters of products. We focus on the recorded music industry as a managerial context, and construct a flexible duration-time model that can be used to capture the dynamic purchase patterns across a broad portfolio of different albums. Our basic...

This article examines how the nature of competition between brands in a therapeutic category changes after generic entry and provide a framework for analyzing the effect of generic entry on consumer welfare that takes into account the generic free riding problem. It demonstrates that changes in competition along dimensions other than retail price--such as competition in research and development...

DESCRIPTION The discrepancy between health care spending and achieved outcomes in the United States has fueled efforts to identify and address situations where unnecessarily expensive therapies are used when less costly, equally effective options are available. The underuse of generic medications is an important example. METHODS A literature review was conducted to answer 5 questions about ge...

Two decades ago, a phenomenon resembling Landau damping was described in the synchronization of globally coupled oscillators: the evidence of a regime where the order parameter decays when linear theory predicts neutral stability for the incoherent state. We here show that such an effect is far more generic, as soon as phase oscillators couple to their mean field according to their natural freq...