Granuloma annulare is a granulomatous disorder of the dermis and subcutaneous tissue, with different clinical types. Generalized granuloma annulare is a rarely encountered clinical entity. We describe a 60-year-old woman with a 4-month history of generalized annular lesions. She had a history of myelocytic leukemia and chronic hepatitis B virus infection. To date, both acute myelocytic leukemia...

The association of granuloma annulare and some neoplasms is controversial. However, there is an increase in the number of case reports and relevant studies supporting the conceptof granuloma annulare being associated with certain types of hematologic neoplasms and solid tumors.Herein, we describe a 54-year-old woman with a 20-month history of generalized annular lesions that did not respond to ...

1. Burns DA. Necrobiotic disorders. In: Burns T, Breathnach S, Cox NH, Griffiths C, editors. Rook’s text book of dermatology. 8th ed. Oxford: Wiley‐Blackwell; 2010. p. 60.1‐60.12. 2. Garg S, Baveja S. Generalized granuloma annulare treated with monthly rifampicin, ofloxacin, and minocycline combination therapy. Indian J Dermatol2013;58:197‐9. 3. Naveen KN, Pai VV, Athanikar SB, Gupta G, Parshwa...

BACKGROUND The localized form of granuloma annulare is usually self-limiting, resolving within 2 years. Generalized granuloma annulare, on the other hand, runs a protracted course, with spontaneous resolution being rare. It is also characterized by a later age of onset, an increased incidence of diabetes mellitus, poor response to therapy, and an increased prevalence of HLA Bw35. OBJECTIVE To...

Granuloma annulare is a benign inflammatory skin lesion of unknown etiology that is usually seen in adults and children and subtypes of it includes localized granuloma annulare, generalized granuloma annulare, subcutaneous granuloma annulare and arcuate dermal erythema. Etiology and pathogenesis of granuloma annulare are obscure, although there is much evidence for an immunologic mechanism. Pre...

Granuloma annulare has been associated with systemic disease including diabetes mellitus. We report a case of a 62-year-old Japanese woman with generalized erythematous granuloma annulare who showed remission after substantial improvement in hyperlipidemia following a strict lipid-lowering diet. The lesion appeared in the lower abdomen one year before current presentation and subsequently sprea...

OBJECTIVES To estimate the prevalence of dyslipidemia (DLP) among individuals with idiopathic granuloma annulare and to examine associations with disease characteristics and comorbidities, such as metabolic syndrome. DESIGN Case-control study using review of medical records from January 2002 through December 2010. SETTING A university hospital and a health care system. PARTICIPANTS Adults...

A 55 year old female came to Skin OPD with extensive pruritic annular papules and plaques over both upper limbs, lower limbs, back and abdomen. Biopsy from one of the lesion confirmed histopathologiclly Granuloma annulare. This case is being presented for its extensive skin involvement without any systemic disorder.