objective refractory convulsive status epilepticus (se) which does not respond to first line drugs (benzodiazepines, phenytoin and phenobarbital) heralds an emergency condition in pediatric neurology which can cause irreparable brain damage. there is no consensus on the choice of drug treatment for refractory generalized  convulsive status epilepticus in children. lidocaine is a valuable forgot...

objective midazolam is a significant and effective drug for control of a life-threatening condition, generalized and partial refractory convulsive status epilepticus. the goal of this study was evaluation of midazolam efficacy for management of this serious disease and its two side effects, hypotension and respiratory failure. materials & methods our study was done using a quasi experimental me...

BACKGROUND AND METHODS Although generalized convulsive status epilepticus is a life-threatening emergency, the best initial drug treatment is uncertain. We conducted a five-year randomized, double-blind, multicenter trial of four intravenous regimens: diazepam (0.15 mg per kilogram of body weight) followed by phenytoin (18 mg per kilogram), lorazepam (0.1 mg per kilogram), phenobarbital (15 mg ...

how to cite this article: fallah r, yadegari y, salmani nodushan m. efficacy and safety of intravenous sodium valproate in convulsive status epilepticus in children in shahid sadoughi hospital. iran. j. child. neurol 2012;6(2):39-44.   objective status epilepticus (se) is the most common pediatric neurologic emergency with high mortality and morbidity. there is no consensus on the drug of choic...

Although there is no consensus over a classification system for status epilepticus, classification is necessary for appropriate management of the condition because effective management depends on the type of status epilepticus. In general, the various systems characterize status epilepticus according to where the seizures arise—from a localized region of the cortex (partial onset) or from both ...

non-convulsive status epilepticus (ncse) may present with several manifestations, many of which may not be obvious. the most important tool for the diagnosis of ncse is the electroencephalograph (eeg) pattern. this is a case report of a boy 9 years of age presenting with severe and continuous headache. he had received chemotherapy for histiocytosis, diagnosed at the age of 3.5 years. no evidenc...

Continuous electroencephalography (EEG) is a major tool for monitoring patients admitted to the intensive care unit after refractory convulsive status epilepticus, following control of movements. We review values different EEG patterns observed in critically ill prognosis and seizure risk, together with proposed criteria non-convulsive epilepticus diagnosis (Salzburg Criteria), scores (Epidemio...

Several medications such as baclofen, amitriptyline and even antiepileptic drugs such as carbamazepine or vigabatrin are known to induce absence status epilepticus in patients with generalized epilepsies. Tiagabine (TGB) is effective in patients with focal epilepsies. However, TGB has also been reported to induce non-convulsive status epilepticus in several patients with focal epilepsies and in...

The risk of long-term mortality and its predictors following convulsive status epilepticus in childhood are uncertain. We report mortality within 8 years after an episode of convulsive status epilepticus, and investigate its predictors from a paediatric, prospective, population-based study from north London, UK. In the current study, we followed-up a cohort previously ascertained during a surve...