نتایج جستجو برای: gemistocytes
تعداد نتایج: 14 فیلتر نتایج به سال:
we report two cases of de novo gemistocytic glioblastomas. in case one, a 35 year male presented with features of raised intracranial pressure and rapid neurological deterioration. in case 2; a 73 year old male presented with rapid neurological deterioration and focal neurological deficits. in both cases imaging findings were suggestive of high grade malignancy involving the brain. this was con...
PURPOSE Some cases of hemichorea-hemiballism (HCHB) are associated with a hyperintense putamen on T1-weighted MR images, the cause of which remains unclear. Our purpose was to determine the cause and significance of these MR signal changes. METHODS We analyzed the clinical and neuroimaging findings in 10 patients with HCHB, focusing on locations of the hyperintense lesions on T1-weighted imag...
OBJECTIVE Although gemistocytic astrocytomas are graded as World Health Organization II astrocytomas, they behave more aggressively than other astrocytomas. Their proliferative potential is low, and it remains an intriguing question why these tumors are so biologically "successful." They show a high mutation rate of the P53 gene, cytological abnormalities, and frequent perivascular mononuclear ...
T1-Weighted MR Images: A Biopsy Sample Re-Examined To determine the pathologic process responsible for the signal intensity changes of hyperintense putamen on T1-weighted MR images (Fig 1A), we had previously performed stereotactic biopsy in a 72year-old man 3 months after the onset of stroke and hemiballism. The results revealed a fragment of gliotic brain tissue with abundant gemistocytes, wh...
We report two cases of de novo Gemistocytic glioblastomas. In case one, a 35 year male presented with features of raised intracranial pressure and rapid neurological deterioration. In case 2; a 73 year old male presented with rapid neurological deterioration and focal neurological deficits. In both cases imaging findings were suggestive of high grade malignancy involving the brain. This was ...
PURPOSE Tumor-infiltrating lymphocytes (TIL) have prognostic significance in many cancers, yet their roles in glioblastoma have not been fully defined. We hypothesized that TILs in glioblastoma are associated with molecular alterations, histologies, and survival. EXPERIMENTAL DESIGN We used data from The Cancer Genome Atlas (TCGA) to investigate molecular, histologic, and clinical correlates ...
Purpose: Tumor-infiltrating lymphocytes (TIL) have prognostic significance in many cancers, yet their roles in glioblastoma have not been fully defined. We hypothesized that TILs in glioblastoma are associated with molecular alterations, histologies, and survival. Experimental Design: We used data from The Cancer Genome Atlas (TCGA) to investigate molecular, histologic, and clinical correlates ...
Video Microscope Robotic Arm-Assisted, Neuronavigation-guided Glioma Resection and Regional Sampling
High-grade gliomas possess internal pathological heterogeneity. Selective sampling of different tumor regions can help in the study of this heterogeneity. In this report, we have described the use of a novel navigation and optical system for the selective regional sampling of a high-grade glioma lesion. A 45-year-old gentleman presented to us with complaints of intermittent frontal headaches fo...
Abstract Background Gemistocytes (GCs) are unique phenotype of reactive astrocytes. In diffuse low-grade gliomas, they associated with grim prognosis. Less is known regarding their pathogenesis and prognostic significance in glioblastoma (GBM). Previous data on-neoplastic central nervous system (CNS) lesions has linked the presence GCs states uncontrolled hyperglycaemia diabetes mellitus type 2...
OBJECTIVE Atypical teratoid rhabdoid tumor is a rare neoplasm with a distinct cytogenetic profile that predominates in infancy. Many cases show predominance of small cells with scanty rhabdoid cells, making recognition of this tumor difficult. We aim at describing our experience with atypical teratoid rhabdoid tumor cases diagnosed over a 6-year period. MATERIAL AND METHOD Clinicopathologic f...
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