aim : the purpose of this study was to assess the incidence of 16bp insertion of intron 3 p53 in gastritis lesion and its correlation with clinicopathological aspects. background : p53 alterations have been implicated in the development of gastric malignancies. patients and methods : 97 gastritis and normal adjacent tissues were investigated for p53 gene analysis using pcr-sequencing of intron3...

objective: to determine the role of global genome methylation in gastritis lesion and its relation with clinicopathologic finding. materials and methods: the study was conducted on 44 gastritis and normal adjacent specimens using a technique composed of restriction enzyme digestion and pyrosequencing known as luma (luminometric methylation assay). at first, dna extracted from gastritis lesion a...

local inflammatory processes in the gastric mucosa are followed by extensive immune cell infiltration, resulting in chronic active gastritis characterized by a marked infiltration of t(h)1 cytokine-producing cd4+ and cd8+t-cells objective. to investigate the correlation between cd4+/cd8+ t-cells in gastric mucosa with endoscopic appearance in chronic gastritis with or without h.pylori infection...

This paper describes the incidence of positive serological tests for autoantibodies to gastric mucosal antigen and to thyroglobulin in patients with chronic gastritis, pernicious anaemia, and postgastrectomy gastritis. The results support the recent concept (British Medical Journal, 1962) that diffuse atrophic gastritis, which is the essential lesion in most cases of pernicious anaemia, may hav...