background: helicobacter pylori may cause many gastrointestinal problems in developing countries such as iran. we aimed to analyze the cost- effectiveness and cost- utility of the test-and-treat and empirical treatment strategies in managing helicobacter pylori infection.            methods: this was a markov based economic evaluation. effectiveness was defined as the symptoms free numbers and ...

The objective of present study is to investigate anti-ulcer activity of Artocarpus heterophyllus Lam. leaves extracts on indomethacin induced ulcers in rats and establish the probable mechanism of antiulcer activity, if any and confirm the validity of claims of the activity as mentioned in texts as traditional medicines. The leaves were extracted with methanol and anti-ulcer activity was evalua...

The effect of an aqueous leaf extract ofAnacardium occidentale on gastric acid secretion was tested in rats. Twenty (20) Wistar albino rats were used for the gastric acid assay experiment. The rats were divided into 2 groups of 10 each. Gastric acid output was determined by continuous perfusion of rat stomach in urethane anesthetized rats. Control gastric acid output was obtained using 0.9% sod...

Fat in small intestine decreases meal-stimulated gastric acid secretion and slows gastric emptying. CCK is a mediator of this inhibitory effect (an enterogastrone). Because intravenously administered peptide YY (PYY) inhibits acid secretion, endogenous PYY released by fat may also be an enterogastrone. Four dogs were equipped with gastric, duodenal, and midgut fistulas. PYY antibody (anti-PYY) ...

Anti gastric ulcer activity of root, stem and leaves of Amaranthus spinosus Linn. was studied against ethanol, hydrochloric acid, indomethacin, stress and pyloric ligation induced gastric ulceration in albino rats. Omeprazole was used as standard anti gastric ulcer drug. Significant anti gastric ulcer activity was noted in root, stem and leaves of Amaranthus spinosus Linn. Root of the plant, ho...

Purpose: To investigate the activity of Feronia elephantum fruit pulp extract (which is used in folk medicine) against indomethacin-induced gastric ulcer in rats. Methods: The fruit pulp was extracted with ethanol and the anti-ulcer activity of the extract in indomethacin-induced gastric ulceration in Swiss albino rats was evaluated. The parameters assessed were pH and acid concentration of gas...

The effect of varying doses of ethanol extract of Aloe vera (Liliaceae) on acute gastric mucosal lesions induced by 0.6 M HCl and acid output was studied in the pylorus ligated and lumen perfuse rats, respectively. Acid secretion was determined by titration of the collected gastric juice to pH 7.0. Intraperitoneal injection of Aloe vera, dose dependently inhibited gastric acid secretion. The pl...