Received August 3, 2007 Abstract Background and Aim: The significance of serum gamma glutamyltransferase activity and its dynamics have not been well investigated in Asian patients with idiopathic neonatal hepatitis. This study aimed to explore the significance in Mainland China. Methods: A retrospective analysis was performed in 38 cases with a diagnosis of idiopathic neonatal hepatitis. Their...

gamma-Glutamyltransferase is widely used as a marker of alcohol intake although its performance is poor. This might be related to other conditions influencing gamma-glutamyltransferase activity. The authors studied determinants of gamma-glutamyltransferase activity in a random sample (n = 6,010) drawn from the general population aged 25-64 years in Finland in 1992. In regression analysis, coffe...

background and aims: post exercise proteinuria and increased urinary gamma-glutamyl transferase (ggt) levels can be indicative of exercise-induced renal damage. the aim of this investigation was to study the effect of one session of intensive training on renal tubular injury markers and compare their values to those 6 hours after training, for evaluating tubular damage after intensive training....

background & objective: there are many common infections and inflammations among people over the world. this demands an affordable and reliable test with high sensitivity/specificity to predict or confirm the diagnosis of such cases in routinely clinical practice. in the present study, we aimed to find any potential correlation between serum levels of ggt and crp- q and/or hs- crp and wbc c...

Compared with controls, patients with alcoholic fatty liver showed a significant increase of gamma-glutamyltransferase activity both in the liver and serum, whereas alkaline phosphatase activity was raised only in the liver but not in the serum. The activities of other enzymes such as aspartate aminotransferase, alanine aminotransferase and glutamate dehydrogenase remained virtually unchanged i...

background elevated serum gamma-glutamyltransferase (ggt) is predictive of various cardiovascular (cv) risk factors including chronic kidney disease (ckd). elevated serum ggt has been recognized in smokers who are likely to develop ckd, but no study has focused on serum ggt and ckd in smokers. objectives the aim of this study was to clarify the associations between cigarette consumption, elevat...

Reference ranges for amniotic fluid alkaline phosphatase, gamma-glutamyltransferase, and 5-nucleotidase are described from 13 to 40 weeks' gestation. Gamma-glutamyltransferase and 5-nucleotidase activities peak early in the second trimester and then decrease to low values. Alkaline phosphatase shows a similar pattern of activity from 13 to 29 weeks' gestation, but thereafter activity increases ...

We compared alkaline phosphatase (EC 3.1.3.1) and gamma-glutamyltransferase (EC 2.3.2.2) activities in sera from children with various hepatic diseases with values for normal children. Although values for both enzymes are above normal in essentially the same liver disorders, the latter is much more specific and sensitive. A single value for alkaline phosphatase, measured at any time during chil...

purpose post exercise proteinuria and increased urinary gamma-glutamyl transferase (ggt) levels can be indicative of exercise-induced renal damage. the aim of this investigation is to study the effect of one session of intensive training on renal damage markers and compare their values to those 6 hours after training. methods in this cross-sectional study with pre- and post-test design, 10 elit...

Gamma-glutamyltransferase activity in serum is shown to be competitively inhibited by the two substrates gamma-glutamyl-4-nitroanilide and glycylglycine. Awareness of this is of importance when one is choosing final reaction conditions for the assay of the enzyme. Gamma-glutamyltransferase probably acts by a "ping-pong bi-bi" kinetic mechanism, which fits with the double competitive substrate i...