Free radicals involved in a number of diseases due to the oxidative damage to DNA, lipids, and proteins and which can result in failure of cellular functions. Dried plant bulbs and leaves methanolic and ethanolic extracts were prepared. Total antioxidant activities of the methanolic extracts of Romulea ramiflora and Gagea fibrosa were determined using β-caroten-linoleic acid assay. Romulea-...

free radicals involved in a number of diseases due to the oxidative damage to dna, lipids, and proteins and which can result in failure of cellular functions. dried plant bulbs and leaves methanolic and ethanolic extracts were prepared. total antioxidant activities of the methanolic extracts of romulea ramiflora and gagea fibrosa were determined using β-caroten-linoleic acid assay. romulea-bulb...

BACKGROUND AND AIMS Gagea is a Eurasian genus of petaloid monocots, with a few species in North Africa, comprising between 70 and approximately 275 species depending on the author. Lloydia (thought to be the closest relative of Gagea) consists of 12-20 species that have a mostly eastern Asian distribution. Delimitation of these genera and their subdivisions are unresolved questions in Liliaceae...

Nuclear genome size, as measured by flow cytometry with propidium iodide, was used to investigate the relationships within the genus Gagea (Liliaceae), mainly from the Netherlands. The basic chromosome number for Gagea is x = 12. The inferred ploidy in the Dutch and German accessions varies from diploid to decaploid. Consequently there is a large range of genome sizes (DNA 2C-values) from 14.9 ...

BACKGROUND Aortic valve (AV) calcification preferentially occurs on the fibrosa side while the ventricularis side remains relatively unaffected. Here, we tested the hypothesis that side-dependent activation of bone morphogenic protein (BMP) pathway in the endothelium of the ventricularis and fibrosa is associated with human AV calcification. METHODS AND RESULTS Human calcified AVs obtained fr...

Aortic valve (AV) calcification is an inflammation driven process that occurs preferentially in the fibrosa. To explore the underlying mechanisms, we investigated if key microRNAs (miRNA) in the AV are differentially expressed due to disturbed blood flow (oscillatory shear (OS)) experienced by the fibrosa compared to the ventricularis. To identify the miRNAs involved, endothelial-enriched RNA w...

One form of renal osteodystrophy secondary to chronic renal failure is the osteitis fibrosa cystica, which is the complication of secondary hyperparathyroidism. Osteitis fibrosa cystica is a histologically benign, tumor-like lesion of bones. Since early diagnosis and treatment of hyperparathyroidism is available nowadays, the development of osteitis fibrosa cystica has become rare. It can only ...

Mitral-aortic intervalvular fibrosa aneurysm is a rare disease entity whose aetiology remains uncertain. Most of the cases reported are believed to be a sequela of infective endocarditis. We present a case of congenital mitralaortic intervalvular fibrosa aneurysm, representing the first patient to be diagnosed at birth in the literature. This report illustrates the imaging features of mitral-ao...

BACKGROUND Secondary involvement of the mitral-aortic intervalvular fibrosa and the anterior mitral leaflet (subaortic structures) can occur in patients with aortic valve endocarditis. The secondary involvement of these structures occurs as a result of direct extension of the infection from the aortic valve or as a result of an infected aortic regurgitant jet striking the ventricular surfaces o...