background:  nowadays mri examinations have been widely used in clinical applications for many diagnoses. the use of contrast agent in mri improves lesion detection and characterization and causes more accurate diagnosis.  objectives: the aim of this study was comparing to optimal dose of magnevist contrast agent in modified t1w se (spin echo), t1w fse (fast spin echo) and t1w gre (gradient ech...

The objective of this study was to quantify microstructural remodeling in peri-infarcted and infarcted porcine myocardium using diffusion tensor MRI (DT-MRI) for the first time. High resolution ex vivo late gadolinium enhanced (LGE) MRI was used to segment the DT-MRI data into normal, peri-infarct and infarcted myocardium. LGE-MRI based segmentation produces regions with significantly different...

OBJECTIVE Early treatment following a first clinical demyelinating event (FCDE) delays further disease activity in patients with multiple sclerosis (MS). This study determined the effects of early versus delayed treatment (DT) with subcutaneous interferon (sc IFN) β-1a 44 μg in patients with an FCDE up to 60 months postrandomisation. METHODS Patients who completed the 24-month double-blind RE...

Purpose: Diffusion weighted MRI (DWI) is influenced by perfusion effects at lower b-values, an effect sometimes termed intravoxel incoherent motion (IVIM). Movement of blood in microvasculature can be modeled as pseudo-diffusion and this perfusion effect can be separately determined if both low (<200 sec/mm) and high b values are used. The purpose of our study was to calculate perfusion fractio...

PURPOSE The aim of this study was to use intravoxel incoherent motion diffusion-weighted imaging to discriminate subtypes of renal neoplasms and to assess agreement between intravoxel incoherent motion (perfusion fraction, fp) and dynamic contrast-enhanced magnetic resonance imaging (MRI) metrics of tumor vascularity. SUBJECTS AND METHODS In this Health Insurance Portability and Accountabilit...

Objective(s): Relevance between magnetic resonance imaging (MRI) relaxation rate and concentration of magnetic nanoparticles determines the capability of a nanomaterial to provide MRI contrast. In the present study, alginate was conjugated to gadolinium/graphene oxide nanocomposite to form gadolinium/graphene oxide/alginate nanocomposite, aiming to investigate its effect on the relevance betwee...

BACKGROUND Q waves and negative T waves are common electrocardiographic (ECG) abnormalities in patients with Hypertrophic Cardiomyopathy (HCM). Several studies correlated ECG findings with presence and extent of fibrosis and hypertrophy; however, their significance remains incompletely clarified. Our study aimed to explain the mechanism behind Q and negative T waves by comparing their positions...

Due to the higher hydrogen solubility and diffusivity, gadolinium sesquioxide (Gd2O3) could be expected as a proton conductive material. In this study, monoclinic Gd2O3 was used evaluate possible conductivity in Ar (?Ar), Ar+4% H2 (?H2), D2 (?D2), Ar+H2O (?H2O), Ar+D2O (?D2O), O2 (?O2) atmospheres temperature range from 500°C 1000°C, understand its application DT fuel system of nuclear fusion r...

background: new treatment modalities are developed with the aim of escalating tumor absorbed dose and simultaneously sparing the normal structures. the use of nanotechnology in cancer treatment offers some possibilities including destroying cancer tumors with minimal damage to healthy tissues. zinc oxide nanoparticles (zno nps) are wide band gap semiconductors and seem to have a good effect on ...