introduction: the coagulation factor 13 has a fundamental role in homeostasis, protective effects on thrombosis, and some other associated diseases. due to increasing the chronic coagulability of major thalassemic patients, this study was conducted with aim determining the prevalence of val34leufxiii polymorphism in the thalassemic patients. materials and methods: the present case-control study...

Introduction: The coagulation factor 13 has a fundamental role in homeostasis, protective effects on thrombosis, and some other associated diseases. Due to increasing the chronic coagulability of major thalassemic patients, this study was conducted with aim determining the prevalence of Val34LeuFXIII polymorphism in the thalassemic patients. Materials and methods: The present case-control stud...

6. Warner D, Mansfield MW, Grant PJ. Coagulation factor XIII and cardiovascular disease in UK Asian patients undergoing coronary angiography. Thromb Haemost 2001; 85: 408-11. 7. Kohler HP, Grant PJ. Clustering of haemostatic risk factors with FXIIIVal34Leu in patients with myocardial infarction. Thromb Haemost 1998; 80: 862. 8. Ariëns RAS, Kohler HP, Mansfield MW, Grant PJ. Subunit antigen and ...

Abstract Background Acute myocardial infarction (AMI) is a leading cause of death and morbidity around the world. Although association between thrombophilia AMI well-established, controversial data are present on thrombophilic polymorphisms AMI. The aim this study was to investigate three including factor V Leiden ( FVL ), MTHFRC677T (methylenetetrahydrofolate reductase), Coagulation XIIIVal34L...

Gene polymorphism refers to a variation in DNA sequence that occurs population with frequency of 1% or higher. Polymorphism may be single nucleotide (SNP) some repetitive sequences (length polymorphism). Several methods can used analyze polymorphism, included Polymerase Chain Reaction (PCR), sequencing from the conventional method more sophisticated such as Next Generation Sequencing (NGS), flu...

We assign a relational structure to any finite algebra in canonical way, using solution sets of equations, and we prove that this is polymorphism-homogeneous if only the itself polymorphism-homogeneous. show polymorphism-homogeneity also equivalent property algebraic (i.e., systems equations) are exactly those tuples closed under centralizer clone algebra. Furthermore, aforementioned properties...

background: molecular components of the dopamine receptor (drd3) play an important role in the pathophysiology of schizophrenia (scz). previous studies have demonstrated an association between the drd3 ser9gly polymorphism and scz but the results have been inconclusive. method: in this study, we investigated this controversial association between the ser9gly (a/g) polymorphism and scz using mal...

background coronary artery disease (cad) is the most common cause of death worldwide. mef2a directly regulates target genes in the process of muscle development. this gene product is a transcription factor. mef2a protein in homodimer or heterodimer forms binds to a/t-rich cis elements with conserved sequence in promoter, regulator, and enhancer of many genes, which are determining in evolution ...

Background: Human cornea expresses functional Fas-ligand capable of killing Fas+ activated lymphocytes. Fas expression is partly regulated by -670 A/G polymorphism in the promoter region of Fas gene. Objective: The aim of the present study is to determine the association between Fas-670A/G polymorphism and survival of corneal transplantation. Methods: In 276 graft recipients who mainly underwen...

Background & Aims: To investigate the association of CFI p.Gly119Arg polymorphism with Age-related macular degeneration (AMD). Materials & Methods: In this case-control study, the association of p.Gly119Arg polymorphism in CFI gene was investigated in 65 patients suffering from AMD and150 healthy age, sex and ethnicity matched unrelated people as control group. Both of the case and cont...