escherichia coli (e. coli) bacteria can damage dna of the gut lining cells and may encourage the development of colon cancer according to recent reports. genetic switches are specific sequence motifs and many of them are drug targets. it is interesting to know motifs and their location in sequences. at the present study, gibbs sampler algorithm was used in order to predict and find functional m...

background: computational identification of phylogenetic motifs helps to understand the knowledge about known functional features that includes catalytic site, substrate binding epitopes, and protein-protein interfaces. furthermore, they are strongly conserved among orthologs, indicating their evolutionary importance. the study aimed to analyze five candidate genes involved in type ii diabetic ...

Escherichia coli (E. coli) bacteria can damage DNA of the gut lining cells and may encourage the development of colon cancer according to recent reports. Genetic switches are specific sequence motifs and many of them are drug targets. It is interesting to know motifs and their location in sequences. At the present study, Gibbs sampler algorithm was used in order to predict and find functional m...

One primary focus of complex systems research has been the topological analysis of the network underlying a complex system. One key question is the size and structure/function of the underlying building blocks. Two proposed building blocks are called motif and functional module. A motif has been defined as a subgraph that occurs significantly more frequently in real-world networks than expected...

Lactoferrin (Lf) is an iron-binding multi-functional glycoprotein which has numerous physiological functions such as iron transportation, anti-microbial activity and immune response. In this study, different in silico approaches were exploited to investigate Lf protein properties in a number of mammalian species. Results showed that the iron-binding site, DNA and RNA-binding sites, signal pepti...

This article addresses the presence and size of basic functional modules (motifs) in complex systems. The current view of motifs is that they are small modules of 3-4 “nodes”, which occur significantly more frequently in real-world networks than expected by chance alone. We show that standard functional blocks used to build real-world circuits where a node is interpreted as a primitive componen...