abstract           introduction: genetic variations in the gene encoding endothelial nitric oxide synthase (enos) enzyme affect the susceptibility to cardiovascular disease. identification of the way these changes affect enos structure and function in laboratory conditions is difficult and time-consuming. thus, it seems essential to perform bioinformatics studies prior to laboratory studies to ...

the main objective of this study was to investigate the environmental impacts of cotton production in golestan province of iran using life cycle assessment methodology. the data used in the study were obtained from cotton farmers with face-to-face questionnaire method during 2011-2012. the questionnaires included total inputs of cotton production in the region and yield weight. environmental im...

Functional Data Analysis (FDA) has recently made considerable progress because of easier access to the data that are essentially in the form of curves. Although functional modeling of Iranian precipitation based on temperature or humidity was done before, here we use functional analysis of variance and covariance to analyze the weather data collected randomly from Iranian weather stations in 20...

Background The aim of this study was to assess the ssociation between human transforming growth factor b receptor,type III (TGFBR3) and idiopathic premature ovarian failure (POF) in a Chinese population. MaterialsAndMethods A total of 112 Chinese women with idiopathic POF and 110 normal controls were examined. DNA samples prepared from blood leukocytes were used as templates for polymerase-chai...

SUMMARY Pipit is a gene-centric interactive visualization tool designed to study structural genomic variations. Through focusing on individual genes as the functional unit, researchers are able to study and generate hypotheses on the biological impact of different structural variations, for instance, the deletion of dosage-sensitive genes or the formation of fusion genes. Pipit is a cross-platf...

UNLABELLED Many existing databases annotate experimentally characterized single nucleotide polymorphisms (SNPs). Each non-synonymous SNP (nsSNP) changes one amino acid in the gene product (single amino acid substitution;SAAS). This change can either affect protein function or be neutral in that respect. Most polymorphisms lack experimental annotation of their functional impact. Here, we introdu...