thrombotic thrombocytopenic purpura is the result of multiple thrombus disseminated in small arterioles throughout the body. principle damage is in the endothelium of small vessels and capillaries. from 1982 to 1999, 28 patients (16 female and 12 male) have been treated for ttp. the outcome was evaluated for risk factors and prognosis. these patients were 18 to 69 years old. all had neurologica...

results of 153 patients, 96.8% received pc and 54.9% transfused ffp during or after surgery. most of the transfusions were done after operation in intensive care unit (icu). also, 20% and 17% of the patients underwent transfusion of more than 6 units of pc and ffp, respectively. the mean left ventricular ejection fraction of the patients was 42.5 ± 10.9%. a significant number of patients had an...

background and objectives: pathogen reduction technologies are among methods to eliminate transfusion transmitted infections. mirasol method using riboflavin in combination with ultraviolet rays is one of them. the aims of this study were to investigate the effectiveness of mirasol method to inactivate some model pathogens as well as examination of the sensitivity of plasma proteins after treat...

background and objective: there is a concern on safety of human fresh frozen plasma (ffp) as it is a source of some medicinal products. the possibility of transmission of blood-borne are reported often due to emerging viruses. there are some pathogen reduction technologies (prt) to inactivate viruses. methylene blue (mb) based method is one of them. the aim of this study was to examine new desi...

fresh frozen plasma (ffp) and prothrombin complex concentrate (pcc) reverse oral anticoagulants such as warfarin. we compared the standard dosage ffp and pcc in terms of efficacy and safety for patients with mechanical heart valves undergoing interventional procedures while receiving warfarin. fifty patients were randomized (25 for each group) with mechanical heart valves [international normali...

PURPOSE To describe a novel methodology by which to measure the Hirschberg ratio (HR) in infants. The methodology does not require fixation on specific points, and measurements are made while infants look naturally at a display. METHODS The HR is calculated automatically from measurements of the direction of the optical axis, the position of the pupil center, and corneal reflexes in video ima...

OBJECTIVE To determine the practice of anaesthesiologists in our institution for intraoperative transfusion of Fresh Frozen Plasma (FFP) and to see whether provider education can reduce the incidence of inappropriate FFP transfusion. MATERIAL AND METHODS A retrospective audit was done for 6 months in all patients who received intraoperative FFP transfusion. The result were compared with recom...