The functional requirements for synthetic tissue substitutes appear deceptively simple: they should provide a porous matrix with interconnecting porosity and surface properties that promote rapid tissue ingrowth; at the same time, they should possess sufficient stiffness, strength and toughness to prevent crushing under physiological loads until full integration and healing are reached. Despite...

This current study reports preparation of Nickel-Gadolinium doped Ceria (Ni-GDC) composite via controlled unidirectional freeze casting of aqueous-based GDC slurry completed with nickel infiltrated into the porous GDC samples. Gadolinium doped ceria powder prepared by gel-combustion synthesis method. The oxide powder was confirmed to be the fluorite-structured of Ce0.8Gd0.2O1.9 solid solution b...

Highly porous titanium with aligned large pores up to 500 μm in size, which is suitable for scaffold applications, was successfully fabricated using the reverse freeze casting method. In this process we have newly developed, the Ti powders migrated spontaneously along the pre-aligned camphene boundaries at a temperature of 45.5°C and formed a titanium-camphene mixture with an aligned structure;...

• Freeze-casting phase-field model including particle size effects is presented. Simulations for various sizes and solidification conditions are conducted. Scaling laws microstructural lengths derived based on simulations. The freeze casting process a novel manufacturing method both near net-shape parts as well directed porous structures employed by filters implants. Depending the choice of liq...

Freeze casting, popularly known as ice templating or freeze gelation, is a mechanical method to fabricate scaffolds of desirable properties and materials. Aerospace engineering, the healthcare sector, manufacturing department, automotive industries are different fields where casting has been used. Bioinspiration refers translation biological systems into new innovative creations. Bioinspired ma...

Background: Since the treatments of long tracheal lesions are associated with some limitations, tissue engineered trachea is considered as an alternative option. This study aimed at preparing a composite scaffold, based on natural and synthetic materials for tracheal tissue engineering. Methods: Nine chitosan silk-based scaffolds were fabricated using three freezing rates (0.5, 1, and 2°C/m...

Structured xylan-based hydrogels, reinforced with cellulose nanocrystals (CNCs), have successfully been prepared from water suspensions by cross-linking during freeze-casting. In order to induce cross-linking during the solidification/sublimation operation, xylan was first oxidized using sodium periodate to introduce dialdehydes. The oxidized xylan was then mixed with CNCs after which the suspe...