نتایج جستجو برای: frailty models
تعداد نتایج: 915874 فیلتر نتایج به سال:
b a c k g r o u n d & aim: the excess hazard rate proposed by andersen and vaeth may underestimate the long-term excess hazard rate for cancer survival. zahl explained the phenomenon by continuous selection of the most robust individuals after diagnosis. he applied correlated inverse gaussian and gamma frailty models to estimate excess intensity and reached a better estimate of the rat...
Background and objectives: Birth spacing is an important variable for identification of fertility acceleration, total fertility rate, and maternal and fetal health. Therefore, special attention has been paid to this issue by researchers in the fields of medical sciences, health, and population. In addition, proper analysis of this concept is of foremost importance. Application of classical anal...
Many populations encountered in survival analysis are often not homogeneous. Individuals are flexible in their susceptibility to causes of death, response to treatment and influence of various risk factors. Ignoring this heterogeneity can result in misleading conclusions. To deal with these problems, the proportional hazard frailty model was introduced. In this paper, the frailty model is ex...
Abstract Background: Although corneal graft may be rejected by the immune system of the recipient it remains as the most successful operation as compared to transplantation of other tissues. Since most patient do not reject the grafts, those who do are in the minority. This study was carried out to assess the usefulness of the cure frailty model for determining the significance of risk facto...
Background and Purpose: Gastric cancer is the third leading cause of mortality in Iran after cardiovascular diseases and accidents. The aim of the present study was to assess survival and it’s affecting factors in gastric cancer patients through using Cox and parametric models along with frailty. Materials and Methods: In this study, the medical records of gastric cancer patients treat...
background: cox proportional hazard (cph) model is the most widely used model for survival analysis. when there are unobserved/unmeasured individuals factor, then the results of the cox proportional hazard model may not be reliable. the purpose of this study was to compare the results of cph and frailty models in breast cancer (bc) patients. methods: a historical cohort study was carried out us...
The ethical, logistical, and biological complications of working with an older population of people inherently limits clinical studies of frailty. The recent development of animal models of frailty, and tools for assessing frailty in animal models provides an invaluable opportunity for frailty research. This review summarizes currently published animal models of frailty including the interleuki...
In survival analysis, frailty models are potential choices for modeling unexplained heterogeneity in a population. This tutorial presents an overview and general framework of frailty modeling and estimation for multiplicative hazards models in the context of biomedical and genetic studies. Other topics in frailty models, such as diagnostic methods for model adequacy and inference in frailty mod...
Introducing a random effect into the Cox model is a useful tool forbuilding hierarchical families of univariate semiparametric regressionsurvival models. Hougaard [1984] used the Laplace transform to buildfrailty models with explicitly defined survival functions and random ef-fects. The family derived from stable distributions was then extended[Aalen, 1992] to frailty va...
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