background: acantholimon gilliati turril(plumbaginaceae) is used in variety of diseases including hepatic ailments in the west region of iran. aim of the study: to investigate the hepatoprotective effect of methanoilc extract (me) of a. gilliati on formaldehyde (fa) induced liver injury in adult male mice.materials and methods: fifty six adult male mice were divided into 8 groups. in control gr...

background and objectives: acantholimon bracteatum (girard) boiss (plumbaginaceae) is used in variety of diseases including hepatic ailments in the west regions of iran. in the present study, the hepatoprotective effect of the methanol extract (me) of a. bracteatum on formaldehyde (fa) induced liver injury has been investigated in adult male mice. methods: fifty six adult male mice were divided...

Background: Acantholimon gilliati Turril(Plumbaginaceae) is used in variety of diseases including hepatic ailments in the west region of Iran. Aim of the study: To investigate the hepatoprotective effect of methanoilc extract (ME) of A. gilliati on formaldehyde (FA) induced liver injury in adult male mice.Materials and methods: Fifty six adult male mice were divided into 8 groups. In control gr...

Background: Acantholimon gilliati Turril(Plumbaginaceae) is used in variety of diseases including hepatic ailments in the west region of Iran. Aim of the study: To investigate the hepatoprotective effect of methanoilc extract (ME) of A. gilliati on formaldehyde (FA) induced liver injury in adult male mice.Materials and methods: Fifty six adult male mice were divided into 8 groups. In control gr...

introduction drug-induced liver injury is a frequent cause of hepatic dysfunction. several drugs have been identified to cause autoimmune hepatitis (aih). environmental chemicals are capable of triggering a certain degree of liver injury. however, toxin induced aih is rare. conclusions chronic (long-term) exposures to dichlorvos can lead to aih. a detailed inquiry of medical history and liver b...

conclusions in conclusion, we have shown that vitamin c administration provides protection against csa-induced injury in rat liver function and may have hepatoprotective role in the patients experiencing csa treatment. background cyclosporine a (csa) is an important immunosuppressive agent; however, its clinical use is limited by several side effects such as hepatotoxicity. vitamin c (ascorbic ...

Background and objectives: Acantholimon bracteatum (Girard) Boiss (Plumbaginaceae) is used in variety of diseases including hepatic ailments in the west regions of Iran. In the present study, the hepatoprotective effect of the methanol extract (ME) of A. bracteatum on formaldehyde (FA) induced liver injury has been investigated in adult male m...

background:methotrexate (mtx) is one of the most commonly used disease-modifying antirheumatic drugs in the treatment of rheumatoid arthritis (ra) which can be associated with toxic effects on different organs. this study was designed to investigate the hepatotoxic effects in ra patients treated with mtx. methods: in this cross-sectional observational study, ra patients who received standard do...

introduction and objectives: tuberculosis (tb) still remains a major health concern both in developing and developed countries. the rate of the liver injury due to anti-tb drugs in developed countries has been reported up to 4%. the goal of this study is to assess the rate and risk factors for anti-tuberculosis drug-induced liver injury (dili). also, a model has been designed to predict dili in...

conclusions hepatotoxicity of halogenated inhalational anesthetics has been well documented in available literature. halothane-induced liver injury was extensively acknowledged; however, the next generation halogenated anesthetics have different molecular structures and associated with less hepatotoxicity. although anesthesia-induced hepatitis is not a common occurrence, we must consider the as...