نتایج جستجو برای: forced degradation

تعداد نتایج: 200159  

Journal: :iranian journal of pharmaceutical research 0
yucel kadioglu department of analytical chemistry, faculty of pharmacy, ataturk university, 25240, erzurum, turkey. alptug atila department of analytical chemistry, faculty of pharmacy, ataturk university, 25240, erzurum, turkey. mehmet gultekin department of chemistry, faculty of science, ataturk university, 25240, erzurum, turkey. nurdan alcan alp department of chemistry, faculty of science, ataturk university, 25240, erzurum, turkey.

the forced degradation study of lidocaine hcl was carried out according to the ich guideline q1a (r2). the degradation conditions were assessed to be hydrolysis, oxidation, photolysis and dry heat during 24 h, 48 h and 72 h and then the samples were investigated by gc-fid method and nuclear magnetic resonance (nmr) spectroscopy. according to these results, the degradation products were not obse...

Journal: :Journal of Analytical & Pharmaceutical Research 2016

Journal: :Biomedical Journal of Scientific and Technical Research 2022

2014
M Blessy Ruchi D. Patel Prajesh N. Prajapati Y.K. Agrawal

Forced degradation is a degradation of new drug substance and drug product at conditions more severe than accelerated conditions. It is required to demonstrate specificity of stability indicating methods and also provides an insight into degradation pathways and degradation products of the drug substance and helps in elucidation of the structure of the degradation products. Forced degradation s...

Journal: :Journal of Liquid Chromatography & Related Technologies 2013

Journal: :International Journal of Applied Pharmaceutics 2018

Journal: :Indian journal of pharmaceutical sciences 2015
Sindhu Narayanan Aruna P Jadhav V J Kadam

Anthraquinones are natural phenolic compounds, which are reported to act as anti-aging, anti-inflammatory, antioxidant, anti-cancer, laxative and antitumor agents. They are abudant in plants like candle bush, aloes, cascara bark and rhubarb. The present work was to observe the effect of different forced degradation conditions by high-performance thin layer chromatography on potential markers i....

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه بیرجند - دانشکده کشاورزی 1390

abstract this study is carried out to determine the chemical composition in the three vegetative stages of the haloxylon sp., degradation parameters, with adding naoh and ca(oh2 ). for this purpose, in may and october and january 2010 enough some haloxylon sp. of the ammary area was prepared. crude protein and ash percentage are decrease, neutral detergent fiber percentage with pragress stage ...

Journal: :Journal of Bioequivalence & Bioavailability 2016

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