The present study sought to investigate whether a single night of partial sleep deprivation (PSD) would alter fasting insulin sensitivity and cephalic phase insulin release (CPIR) in humans. A rise in circulating insulin in response to food-related sensory stimulation may prepare tissues to break down ingested glucose, e.g. by stimulating rate-limiting glycolytic enzymes. In addition, given ins...

This pilot study deals with the possibilities of a Continuous Glucose Monitoring System (CGMS, Minimed- Medtronic) to optimize insulin substitution. Ten persons with type 1 diabetes mellitus treated by means of an insulin pump entered the study and eight of them completed the protocol. CGMS was introduced for a period of 5 days. The standard dinner (60 g of carbohydrates) and overnight fasting ...

This study aims to investigate the effect of fasting time on measuring blood glucose levels in mice. Fasting blood glucose levels were analyzed after 12 h daytime fasting or 12 h night fasting. The results from four mouse models demonstrate that the variation of fasting blood glucose in daytime fasting was smaller than fasting overnight. Our results demonstrate that conducting daytime-fasting v...

OBJECTIVE Fibroblast growth factor (FGF)-21 is an endocrine factor with potent metabolic effects. Its day-night patterns of secretion and/or its physiological response to energy deprivation and relationship to free fatty acids (FFAs) and/or leptin remain to be fully elucidated. We aim to elucidate day-night pattern of FGF-21 levels and its relationship to FFA, to assess whether energy deprivati...

BACKGROUND Disturbed sleep and nocturnal altered breathing are related to disturbances of glucose metabolism. The present uncontrolled observational study explores the role of these factors on the variability of fasting glycemia. METHODS The number and duration of nocturnal awakenings and the fasting glycemia of 97 patients with type 2 diabetes treated with diet, metformin, or gliptins were r...

an experiment was conducted to evaluate the feeding value of date pits in broiler chickens. one hundred sixty eight male broiler chicks (ross 308) from 1 to 42 days of age were used. experimental design was crd, in a factorial arrangement of 4 replicates per treatment. the factors included: 3 levels of date pits (10, 20 and 30%) either with or without multi enzyme supplementation. a control die...

Objective: The purpose of this study was with a multifaceted intervention model improve the nutritional status of elderly people living in residential homes to increase their energy intake and to maintain improvements over time. Setting: Three different municipal residential homes in the south-east of Sweden. Participants: The study population consisted of 67 elderly people. A within-subjects d...

Adaptive Intelligent Tutoring Systems (ITS) aim at helping students going through the resolution of a given problem in a principled way according to the desired outcomes, the intrinsic capabilities of the student, and the particular context in which the exercise takes place. These systems should be capable of acting according to mistakes, boredness, distractions, etc. Several works propose diff...

Humans and animals demonstrate diurnal rhythms in physiology and behavior, which are generated by the circadian pacemaker, located in the supra-chiasmatic nucleus (SCN). The endogenous diurnal rhythm of the SCN is synchronized to the diurnal cycle most effectively by light. However, light also influences the SCN and its output instantaneously, as is demonstrated for the immediate effects of lig...