Introduction: High levels of homocysteine (Hcy) might accelerate dopaminergic cell death through oxidative stress and excitotoxicity. Folate plays an important role in the control of plasma levels of Hcy. In this study, effect of supplementation with folic acid on the 6-hydroxydopamine (6-OHDA)-induced Parkinsonism in rat and also serum level of Hcy was investigated. Methods: Rats were fed ...

the purpose of this study was to investigate the effects of short-term creatine monohydrate (cr) and folic acid (fa) supplementation on homocysteine (hcy) levels in young active males. eighteen young male soccer players (21.11±2.02 years, vo2max 56.51±2.31, hcy 13.45±0.59) volunteered to participate in this study. they were randomly divided into creatine monohydrate (n=6), folic acid (n=6) and ...

this study presented a mini review on folic acid deficiency and recommendations for its supplementation in thalassemia intermedia (ti). ti is a clinical condition which lies between thalassemia major and thalassemia minor. although ti patients may not need regular blood transfusion, precise diagnosis and management are critical for the prevention of clinical complications and quality of life im...

Folic acid plays a basic role in fetal growth, development and prevents fetalmalformations. Pregnant woman's perception regarding folic supplementation is critical

objective: an association between high homocysteine levels and proteinuria in diabetic nephropathy has been shown. on the other hand, supplementation with folic acid lowers homocysteine concentration. we have studied the effects of folic acid supplementation on proteinuria in type 2 diabetic patients with overt proteinuria. materials and methods: forty five (29 men and 16 women) type 2 diabetic...

Although there is accumulating evidence regarding the additional protective effect of folic acid against adverse pregnancy outcomes other than neural tube defects, these effects have not been elucidated in detail. We evaluated whether folic acid supplementation is associated with favorable maternal and fetal outcomes. This was a secondary analysis of 215 pregnant women who were enrolled in our ...

Objective: An association between high homocysteine levels and proteinuria in diabetic nephropathy has been shown. On the other hand, supplementation with folic acid lowers homocysteine concentration. We have studied the effects of folic acid supplementation on proteinuria in type 2 diabetic patients with overt proteinuria. Materials and Methods: Forty five (29 men and 16 women) type 2 diabe...

Folic acid supplementation may prevent the development of cancer in normal tissues but may promote the progression of established (pre)neoplastic lesions. However, whether or not folic acid supplementation can promote the progression of established (pre)neoplastic mammary lesions is unknown. This is a critically important issue because breast cancer patients and survivors in North America are l...