Endocytosis of ligand-activated plasma membrane receptors has been shown to contribute to the regulation of their downstream signaling. beta-arrestins interact with the phosphorylated tail of activated receptors and act as scaffolds for the recruitment of adaptor proteins and clathrin, that constitute the machinery used for receptor endocytosis. Visual- and beta-arrestins have a two-lobe, immun...

The purpose of this article is two fold. First, we show how quasi-periodic solutions for theN-body problem can be constructed by variational methods. We illustrate this by constructing uncountably many quasi-periodic solutions for the fourand six-body problems with equal masses. Second, we show by examples that a system of N masses can possess infinitely many simple or multiple choreographic so...

any 3d seismic survey can have an acquisition footprint. acquisition footprint is an expression of the surface geometry (most common on land data) that leaves an imprint on the stack of 3d seismic data. often we recognize it as amplitude and phase variations on time slices, which of course display the amplitudes within our data set at a specified two way time (cordsen, 2004). on the other hand,...

abstract in this presentation, a case of bilateral choroidal folds in patient with diabetic retinopathy was reported. by our knowledge, this case presentation is the first report of choroidal folds in diabetic retinopathy, which bilateral symmetric and horizontal folds arranged in macula. the thick choroid that is developed in diabetics may be a cause of these folds but the source of difference...