With the advancement in metabolic engineering technologies, reconstruction the genome of a host organism to achieve desired phenotypes for example, to optimize the production of metabolites can be made. However, due to the complexity and size of the genome scale metabolic network, significant components tend to be invisible. This research utilizes Flux Balance Analysis (FBA) to search the essen...

This and the accompanying paper present an overview of the face and body animation object in the MPEG-4 Version 2 standard. The MPEG-4 standard includes the representation, compression of virtual human models and their interface with other MPEG-4 objects, with bit rate requirements as low as 1 Kbit/second. In this paper, we give an overview of animation techniques for the FBA object, and in the...

Biology is going through a paradigm shift from reductionist to holistic, systems-based approaches. The complete genome sequence for a number of organisms is available and the analysis of genome sequence data is proving very useful. Thus, genome sequencing projects and bioinformatic analyses are leading to a complete 'parts catalog' of the molecular components in many organisms. The next challen...

New experimental results on bacterial growth inspire a novel top-down approach to study cell metabolism, combining mass balance and proteomic constraints to extend and complement Flux Balance Analysis. We introduce here Constrained Allocation Flux Balance Analysis, CAFBA, in which the biosynthetic costs associated to growth are accounted for in an effective way through a single additional genom...

Evolutionary forces will affect the structure of metabolic networks and their dynamic behaviors. To examine this hypothesis, in this work we investigate the relationship between the complexity of the metabolic glycolytic networks and the stability of the networks in different cells. By deriving the stoichiometrix from the FBA methods, we develop the models for Sce, Dmgr, Dsmi and Pic in fungi. ...

This and the accompanying paper present an overview of the face and body animation object in the MPEG-4 Version 2 standard. The MPEG-4 standard includes the representation, compression of virtual human models and their interface with other MPEG-4 objects, with bitrate requirements as low as 1 Kbit/second. In this paper we give an overview of geometrical modeling techniques for the FBA object, a...