fluid invasion from water-based drilling mud (wbdm) into the shale formations causes swelling,high pressure zone near the wellbore wall, and eventually wellbore instability problems duringdrilling operations. for the stability of the wellbore, physical plugging of nanoscale pore throats couldbe considered as a logical approach toward avoiding the fluid invasion into the shale formation. thispap...

Fluid invasion from water-based drilling mud (WBDM) into the shale formations causes swelling, high pressure zone near the wellbore wall, and eventually wellbore instability problems during drilling operations. For the stability of the wellbore, physical plugging of nanoscale pore throats could be considered as a logical approach toward avoiding the fluid invasion into the shale formation. This...

Hepatocellular carcinoma (HCC) is the most common form of liver cancer (~80%), and it is one of the few cancer types with rising incidence in the United States. This highly invasive cancer is very difficult to detect until its later stages, resulting in limited treatment options and low survival rates. There is a dearth of knowledge regarding the mechanisms associated with the effects of biomec...

We study experimentally how wettability impacts fluid–fluid displacement patterns in granular media. We inject a low-viscosity fluid (air) into a thin bed of glass beads initially saturated with a more-viscous fluid (a water/glycerol mixture). Chemical treatment of glass surfaces allows us to control the wetting properties of the medium and modify the contact angle θ from 5 deg (drainage) to 12...

UNLABELLED Amniotic fluid Gram stain and culture have been utilized as laboratory tests of microbial invasion of the amniotic cavity. The Gram stain of amniotic fluid has a low sensitivity in the detection of clinical infection or microbial invasion of the amniotic cavity, and amniotic fluid culture results are not immediately available for management decisions. Glucose concentration is used to...

The growth and progression of most solid tumors depend on the initial transformation of the cancer cells and their response to stroma-associated signaling in the tumor microenvironment (1). Previously, research on the tumor microenvironment has focused primarily on tumor-stromal interactions (1-2). However, the tumor microenvironment also includes a variety of biophysical forces, whose effects ...

Cementing is an essential part of every drilling operation. Protection of the wellbore from formation fluid invasion is one of the primary tasks of a cement job. Failure in this task results in catastrophic events, such as blow outs. Hence, in order to save the well and avoid risky and operationally difficult remedial cementing, slurry must be optimized to be resistant against gas migration phe...

We investigate the displacement of one fluid by another in a deformable medium with pore-scale disorder. We develop a model that captures the dynamic pressure redistribution at the invasion front and the feedback between fluid invasion and microstructure rearrangement. Our results suggest how to collapse the transition between invasion percolation and viscous fingering in the presence of quench...