5-aminolevulinic acid (ALA), a new plant growth regulator, can inhibit stomatal closure by reducing H2O2 accumulation in guard cells. Flavonols are a main kind of flavonoids and have been proposed as H2O2 scavengers in guard cells. 5-aminolevulinic acid can significantly improve flavonoids accumulation in plants. However, whether ALA increases flavonols content in guard cells and the role of fl...

Wild marigold (Tagetes minuta), a flowering plant of the family Asteraceae contains compounds of pharmaceutical and nutritional importance especially essential oils and flavonols. Identification, characterization of flavonols and determination of their antibacterial activity were major objectives of the current study. The isolation and purification of flavonols was accomplished using chromatogr...

Glucuronidation is often recognized as one of the rate-determining factors that limit the bioavailability of flavonols. Hence, design and synthesis of more bioavailable flavonols would benefit from the establishment of predictive models of glucuronidation using kinetic parameters [e.g., K(m), V(max), intrinsic clearance (CL(int)) = V(max)/K(m)] derived for flavonols. This article aims to constr...

Farinose exudates on fronds of Notholaena species are known to consist of flavonoid aglycones. These are predominantly methylated flavones and flavonols, sometimes chalcones and dihydrochalcones. Flavonols with unusual properties, excreted as major farina components by some species, have been found to be derivatives of methylated flavonols, esterified in position 8 with butyric or acetic acids,...

The glycosylation of five different flavonols, fisetin, quercetin, myricetin, kaempferol, and 3-hydroxyflavone, was achieved by applying YjiC. 3-Hydroxyflavone was selected as a probe for in vitro glycorandomization of all flavonols using diverse nucleotide diphosphate-d/l-sugars. This study unlocked the possibilities of the glycodiversification of flavonols and the generation of novel compound...

four chinese pomegranate (punica granatum l.) cultivars were analyzed for their individual flavonols and flavones (in fruit peel extracts) using high performance liquid chromatography (hplc), with changes in flavonols and flavones as occurring during fruit development. the results revealed the presence of kaempferol, quercetin, myricetin, luteolin, and apigenin in all the four cultivars. in add...

the non-enzymatic glycation of low density lipoprotein (ldl) is a naturally occurring chemical modification of apolipoprotein b as a result of condensation between lysine residues and glucose. glycated ldl is poorly recognized by ldl receptors and initiates different processes that can be considered proatherogenic. thus, ldl glycation may contribute in the increased atherosclerotic risk of pati...

A recent meta-analysis of prospective cohort studies suggests that high dietary intakes of flavonols are associated with a significantly lower risk of coronary heart disease mortality. The major dietary sources of flavonols such as quercetin, kaempferol, and isorhamnetin are tomatoes, onions, kale, broccoli, celery, apples, and cherries, while catechins are concentrated in tea and red wine. 3 N...