In botany textbooks the farinose coating on leaves and inflorescences of many Primula species is still often said to "consist of flavone". We have shown earlier [1, 2] that it is in fact formed by varying amounts of unsubstituted flavone (at least 50%), 5-hydroxy flavone and 2'-hydroxy flavone, accompanied in many species by 5,8-dihydroxy flavone (primetin) and 5,2'-dihydroxyflavone. Further co...

High-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry was used to identify flavone aglycones and glycosides in soybean pods. Tandem mass spectrometry (MS-MS and MS-MS-MS) and photodiode array detection were also utilized in flavone characterization. A total of seven flavone aglycones and glycosides were identified. Among them three flavone aglycones--...

In this study, we report the effects of a non-antioxidant flavonoid flavone on vascular reactivity in Wistar-Kyoto (WKY) rat isolated aortae. Whether flavone directly modulates vascular reactivity in spontaneously hypertensive rat (SHR) and streptozotocin-induced diabetic-WKY rat isolated aortae was also determined. Thoracic aortic rings were mounted in organ chambers and exposed to various dru...

This study investigates the effects of 2-phenyl-1-benzopyran-4-one (flavone) on DENV-2 infectivity in Vero cells. Virus adsorption and attachment and intracellular virus replication were investigated using a foci forming unit assay (FFUA) and quantitative RT-PCR, respectively. Addition of flavone (100 μg/mL) significantly increased the number of DENV-2 foci by 35.66% ± 1.52 and 49.66% ± 2.51 wh...

6, 8–trimethoxy Flavone and 3, 5–dihydroxy-6, 7, 8–trimethoxy Flavone Concentrations in Rat Colon Tissue C. L. Whitted, V. E. Palau, R. D. Torrenegra, O. E. Rodriguez, S. Harirforoosh East Tennessee State University, Universidad de Ciencias Aplicadas y Ambientales, Universidad del Bosque Purpose In vitro antineoplastic activity against colon cancer cell lines has been previously shown [1]for is...

Our previous study demonstrated that flavone inhibits vascular contractions by decreasing the phosphorylation levelof the myosin phosphatase target subunit (MYPT1). In the present study, we hypothesized that flavone attenuates vascular contractions through the inhibition of the RhoA/Rho kinase pathway. Rat aortic rings were denuded of endothelium, mounted in organ baths, and contracted with eit...

Flavonoids are widely occurring in our diet. In this study, the effects of nine flavonoids on acetaminophen (APAP) oxidation and related cytochrome P450 (P450) enzyme activities were investigated. With rat liver microsomes, APAP oxidation was stimulated 2- to 4-fold by 50 microM flavone or tangeretin and inhibited 65% by myricetin or quercetin. Only a slight inhibition of APAP oxidation was cau...

Flavone, dextrose and long swim stress exhibited antinociception. Degree of antinociception was greater with long swim stress as compared to flavone or dextrose. Combination of these treatments resulted in potentiation of antinociception. Naloxone (opioid antagonist; 5 mg/kg i.p.) antagonised flavone or long stress induced antinociception showing opioid medicated mechanism, however, failed to r...

Knowledge of the inheritance of C-glycosyl flavone synthesis in maize (Zea mays L.) silk tissues has been acquired through detailed genetic studies involving primarily germplasm from the Corn Belt Dent race. To test the robustness of this genetic knowledge, we examined C-glycosyl flavone synthesis in a genetically distinct germplasm pool, popcorn. C-glycosyl flavone profiles and levels and the ...

Z. Naturforsch. 50c, 345-352 (1995); received January 27/February 20, 1995 Liverworts, Frullania, Flavone Aglycones, Acylated Flavone Glycosides, Chemotaxonomy From Frullania teneriffae 5 known flavone aglycones and 6 flavone glycosides were iso­ lated, among them the new 6-OH-luteolin-6-0-ß-D-glucoside-7-0-ß-D-glueoside-6'"-(3-hydroxy-3-methylglutaroylester). F. cesatiana contains 2 flavone-di...