Extraintestinal pathogenic Escherichia coli (ExPEC) acts as a commensal within the mammalian gut but can induce pathology upon dissemination to other host environments such as the urinary tract and bloodstream. ExPEC genomes are likely shaped by evolutionary forces encountered within the gut, where the bacteria spend much of their time, provoking the question of how their extraintestinal virule...

Sixty strains of Escherichia coli, isolated by hemoculture, from septicemic Brazilian patients were evaluated to determine their serogroup and invasivity to Vero cells. All 60 patients died within 2 days of hospitalization. Furthermore, the molecular study of the following extraintestinal pathogenic E. coli-associated virulence factor (VF) genes was performed by PCR: i) adhesins: type 1 fimbria...

We studied the pathogenic role of host and Escherichia coli virulence factors in the development of E. coli bacteremia in patients with acute cholangitis (AC) or upper urinary tract infection (UTI). Isolates recovered from 75 adult patients consecutively admitted to the hospital with E. coli bacteremia caused by AC (n=24) or upper UTI (n=51) were evaluated, as were 30 fecal strains isolated fro...

In this study, virulence factors such as serum resistance, aerobactin iron uptake systems, adhesins (type 1 fimbria, P S afimbrial adhesins), haemolysine, uropathogenic spesific protein and cytotoxic necrotizing factor in 45 Escherichia coli isolates from dogs cats with urinary tract genital system infections, were investigated by both phenotypic methods molecular methods. PCR examinations of E...

Background Escherichia coli is among the most common uropathogens. Increased antibiotic resistance in Gram negative bacilli global concern. Alternative therapeutic options including vaccines against uropathogenic E. (UPEC) have been developed. In this study, we compared genotypic characteristics and antimicrobial susceptibility of UPEC according to phylogenetic groups. Methods We retrospectivel...