background and aims. the aim of this study was to evaluate the effect of dilution and curing methods of an etch-and-rinse adhesive and a self-etching primer from the same manufacturer at early exposure time on cytotoxicity of primary hu-man gingival fibroblasts. materials and methods. primary human gingival fibroblasts were exposed to different dilutions of adper single bond (asb) and adper pro...

Background and Objective: In recent years, due to increasing number of patients with non-healing skin ulcers, skin substitutes have been used. Skin substitutes contain living cells causing faster and more effective wound healing. Therefore, research on the use of autologous and allogeneic cells such as fibroblasts in skin substitutes has attracted attentions. However, there are...

objectives : platelet preparations are commonly used to enhance bone and soft tissue regeneration. considering the existing controversies on the efficacy of platelet products for tissue regeneration, more in vitro studies are required. the aim of the present study was to compare the in vitro effects of plasma rich in growth factors (prgf) and platelet-rich fibrin (prf) on proliferation and viab...

fibroblasts could be considered as connective tissue cells that are morphologically heterogeneous with diverse functions depending on their location and activity. these cells play critical role in health and disease such as cancer and wound by production of collagen, fibronectin, cytokines and growth factors. absence of insulin and other growth factors in serum deprivation condition and similar...

this study aimed to evaluate the cellular toxicity of two newly-released acrylic resins (futura gen and gc reline hard) in comparison with the conventional heat-cure resin (meliodent).sample discs from each acrylic resin were placed in 24-well culture plates along with l929 mouse fibroblast cell line. a mixture of the rpmi 1640 medium, antibiotics and 10% fbs was added to the plates and the spe...

conclusions trichloroacetic acid and autologous fibroblast can be considered as therapeutic choice for recalcitrant diabetic foot ulcer. introduction foot ulcer, with a prevalence of 15% in general population, is one of the main complications in patients with diabetes. so far, different therapeutic methods have been provided for the treatment of foot ulcers. when no response to the standard tre...

collagens are the most abundant proteins in the human body. their main function is to provide structural and mechanical support for the tissues, but they are also involved in a number of other biological functions including cell attachment, migration and differentiation. collagens and gelatins are widely used in pharmaceutical and medical applications. every year, more than 50,000 tons of colla...

context connective tissue cells include fibroblasts, chondrocytes, adipocyte, and osteocytes. these cells are specialized for the secretion of collagenous extracellular matrix and are responsible for the architectural framework of the human body. evidence acquisition connective tissue cells play a central role in supporting as well as repairing tissues and organs. fibroblast cell therapy could ...

Fibroblasts could be considered as connective tissue cells that are morphologically heterogeneous with diverse functions depending on their location and activity. These cells play critical role in health and disease such as cancer and wound by Production of collagen, fibronectin, cytokines and growth factors. Absence of insulin and other growth factors in serum deprivation condition and similar...

conclusions based on the results of the current study, it was concluded that aloe vera, licorice and mint extracts had synergistic effects on the viability of dermal fibroblasts; in addition, the combination of aloe vera and licorice with either henna or myrtle, and aloe vera and mint with either cedar or ginger resulted in synergistic effects on viability of dermal fibroblasts. the third categ...