the ultimate goal of the periodontal treatments is a regeneration of periodontium. recently, laser irradiations are commonly used to improve wound repair. because of many controversies about the effects of laser on soft tissue regeneration, more in vitro studies are still needed. the aim of the present in vitro study was to compare the effects of different doses of er:yag (erbium-doped:yttrium,...

Achillea eriophora D.C. (Asteraceae), an endemic species in Iran, is used extensively in Iranian folk medicine to treat various ailments, including gastrointestinal disorders, skin inflammations and wound healing. The present study was aimed to investigate the effects of the methanolic extract of  A. eriophora leaves on the stimulation of human fibroblast cell proliferation and migration as two ...

BACKGROUND Wound healing is a complex and dynamic process following damage in tissue structures. Due to extensive skin damage caused by burn injuries, this study determined the role of human adult peripheral and umbilical cord blood platelet-rich plasma on proliferation and migration in human skin fibroblasts. METHODS Platelet-rich plasma (5, 10, 15, 20 and 50% PRP) from human umbilica...

Objective(s): Umbilical cord blood is a good source of the mesenchymal stem cells that can be banked, expanded and used in regenerative medicine.  The objective of this study was to test whether amniotic membrane extract, as a rich source of growth factors such as basic-fibroblast growth factor, can promote the proliferation potential of the umbilical cord mesenchymal stem cells. Materials and ...

objective(s): umbilical cord blood is a good source of the mesenchymal stem cells that can be banked, expanded and used in regenerative medicine.  the objective of this study was to test whether amniotic membrane extract, as a rich source of growth factors such as basic-fibroblast growth factor, can promote the proliferation potential of the umbilical cord mesenchymal stem cells. materials and ...

in this study, we have investigated the proliferative response of human dermal fibroblasts isolated from normal and psoriatic individuals to different cytokines. we found that il-1, tnf (α) and egf are stimulatory whereas ifn « and 1 both showed inhibitory activity on fibroblast proliferation. il-6 a more recently described cytokine, showed no detectable effects on cell proliferation. investiga...

background: camellia sinensis and zataria multiflora as the potent antioxidants and anti-inflammations are crucial in the management of wound therapy. lipopolysaccharide (lps) was used for the proliferative potential on fibroblast cells and induction of inflammatory mediators. objective: we examined the effects of lps and herbal extracts combination in order to identify their mechanisms of acti...

In this study, we have investigated the proliferative response of human dermal fibroblasts isolated from normal and psoriatic individuals to different cytokines. We found that IL-1, TNF (α) and EGF are stimulatory whereas IFN « and 1 both showed inhibitory activity on fibroblast proliferation. IL-6 a more recently described cytokine, showed no detectable effects on cell proliferation. Inve...

Previous studies indicate that organ fibroblasts play an important role in wound healing, collagen production, remodeling processes and pathogenesis of progressive heart, lung, renal and hepatic fibrotic diseases. Several studies suggest a possible inhibitory role for adenosine in the regulation of fibroblast proliferation. The effect of adenosine A2 agonists on proliferation and differentiatio...

background: norepinephrine plays a trophic role in the control of cell replication and differentiation in target cells that express adrenergic receptors. methods: in this study, we have tested the influence of infraphysiological, physiological and supraphysiological concentrations (0.0001 nm, 1 nm, 10000 nm) of human norepinephrine on the proliferation of breast cancer cells (human breast adeno...