BACKGROUND The trichothecene mycotoxin deoxynivalenol (DON) may be concentrated in distillers dried grains with solubles (DDGS; a co-product of fuel ethanol fermentation) when grain containing DON is used to produce fuel ethanol. Even low levels of DON (≤ 5 ppm) in DDGS sold as feed pose a significant threat to the health of monogastric animals. New and improved strategies to reduce DON in DDGS...

Fusarium graminearum, the causative agent of wheat head blight, produces the trichothecene deoxynivalenol (DON). DON acts as a protein synthesis inhibitor and is a significant factor contributing to the disease. However, acetylation of the C-3 hydroxyl group of a number of different trichothecenes reduces the toxicity to yeast as well as to the singlecelled plant, Chlamydomonas, suggesting that...

The trichothecene 3-O-acetyltransferase gene (FgTri101) required for trichothecene production by Fusarium graminearum is located between the phosphate permease gene (pho5) and the UTP-ammonia ligase gene (ura7). We have cloned and sequenced the pho5-to-ura7 regions from three trichothecene nonproducing Fusarium (i.e., F. oxysporum, F. moniliforme, and Fusarium species IFO 7772) that belong to t...

Fusarium graminearum is causal agent of economically catastrophic disease of cereal Fusarium Head Blight (FHB) around the world. In addition to causing a loss of yield, this fungus causes serious threats to humans and animals due to the contamination of grain with the trichothecene mycotoxin. TRI101 gene, a Fusarium spp. gene, encodes an enzyme that transfers an acetyl group to the C3 hydroxyl ...

fusarium graminearum is causal agent of economically catastrophic disease of cereal fusarium head blight (fhb) around the world. in addition to causing a loss of yield, this fungus causes serious threats to humans and animals due to the contamination of grain with the trichothecene mycotoxin. tri101 gene, a fusarium spp. gene, encodes an enzyme that transfers an acetyl group to the c3 hydroxyl ...