1 Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan 2 Stroke Centre, Aichi Medical University, Aichi 480-1195, Japan 3 Laboratory for Motor Neuron Disease, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan 4 CREST, Japan Science and Technology Agency, 4-1-8, Honcho, Kawaguchi, Saitama 332-0012, Japan 5 Department of Neurology, Kyoto Univer...

Temporal lobe epilepsy is a common form of drug-resistant epilepsy that sometimes responds to dietary manipulation such as the ‘ketogenic diet’. Here we have investigated the effects of the glycolytic inhibitor 2-deoxy-D-glucose (2DG) in the rat kindling model of temporal lobe epilepsy. We show that 2DG potently reduces the progression of kindling and blocks seizure-induced increases in the exp...

Whole-brain voxel-based unbiased resting state functional connectivity was analysed in 418 subjects with autism and 509 matched typically developing individuals. We identified a key system in the middle temporal gyrus/superior temporal sulcus region that has reduced cortical functional connectivity (and increased with the medial thalamus), which is implicated in face expression processing invol...

Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee, DD1 5EH, Scotland, UK Running title: Chemical Validation of Trypanothione Synthetase Address correspondence to: Julie A. Frearson, College of Life Sciences, James Black Centre, University of Dundee, Dow Street, Dundee, DD1 5EH. Tel: +44 1382 386247; Fax: +44 1382 386373; E-mail: j.a.frea...

Journal of Microbiology & Biology Education Volume 14, Number 2 252 ©2013 Author(s). Published by the American Society for Microbiology. This is an Open Access article distributed under the terms of the a Creative Commons Attribution – Noncommercial – Share Alike 3.0 Unported License (http://creativecommons.org/licenses/by-nc-sa/3.0/), which permits unrestricted non-commercial use and distribut...

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Production of mouse h u m a n hybrids by fusion of mouse myeloma cells with human lymphoid cells has been well documented since the early studies of Schwaber and Cohen (1, 2). These hybrids do, however, lack stability and display a preferential loss of h u m a n chromosomes in the days after fusion (3) in a manner that appears to be nonrandom (4, 5). Their chromosomal instability has proved val...

* corresponding author: tel 44 1382 385823 fax 44-1382 344211 [email protected] © 2013. Published by The Company of Biologists Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0), which permits unrestricted non-commercial use, distribution and reproductio...

Novel species of fungi described in this study include those from various countries as follows: Antartica , Cladosporium austrolitorale coastal sea sand. Australia Austroboletus yourkae on soil, Crepidotus innuopurpureus dead wood, Curvularia stenotaphri roots and leaves Stenotaphrum secundatum Thecaphora stajsicii capsules Oxalis radicosa. Belgium Paraxerochrysium coryli (incl. gen. nov.) Cory...