Fractionation of methylene chloride extracts of the resin of Ferula vesceritensis and F. sinaica afforded three sesquiterpene coumarins and a glucose derivative. One of them was a sesquiterpene with a rare carbon skeleton. The structures of these compounds were determined by extensive NMR studies, including DEPT, COSY, NOE, HMQC, and HMBC.

re-investigation of the methylene chloride extract of the roots of ferula sinaica gave ferusinol, a new sesquiterpene coumarin with a rare carbon skeleton, and samarcandin diastereomer. the structures elucidation were determined by ms, 1h- 13c-1d and 2d nmr spectral data.

Re-investigation of the methylene chloride extract of the roots of Ferula sinaica gave ferusinol, a new sesquiterpene coumarin with a rare carbon skeleton, and samarcandin diastereomer. The structures elucidation were determined by MS, 1H- 13C-1D and 2D NMR spectral data.

Re-investigation of the methylene chloride extract of the roots of Ferula sinaica gave ferusinol, a new sesquiterpene coumarin with a rare carbon skeleton, and samarcandin diastereomer. The structures elucidation were determined by MS, 1H- 13C-1D and 2D NMR spectral data.

The medicinal plant Ferula has been widely used in Asian medicine, especially in Uyghur medicine in Xinjiang, China. Given that various substitutes and closely related species have similar morphological characteristics, Ferula is difficult to distinguish based on morphology alone, thereby causing confusion and threatening the safe use of Ferula. In this study, internal transcribed spacer 2 (ITS...

Objective: This study is to investigate the antioxidant and antitumor effects of the extract fractions of the Ferula sinkiangensis K. M. Shen. Methods: Four different fractions of the Ferula sinkiangensis K. M. Shen were obtained by the extraction with petroleum ether, ethyl acetate, n-butanol, and methanol, respectively, which were used to treat the HCT116, Caco-2, HepG2, and MFC cells. Free r...

Polyphenols constitute a distinct group of natural compounds of medicinal importance exhibiting wide range of physiological activities as antioxidant, immunestimulant, antitumor and antiparasitic. Yellow fever and dengue fever are mosquito-borne infectious diseases transmitted by Aedes aegyptii, the presence of yellow fever in Sudan and dengue fever in Saudi Arabia are threats to Egypt with the...

The present study investigated the in vitro antiprotozoal activity of sixteen selected medicinal plants. Plant materials were extracted with methanol and screened in vitro against erythrocytic schizonts of Plasmodium falciparum, intracellular amastigotes of Leishmania infantum and Trypanosoma cruzi and free trypomastigotes of T. brucei. Cytotoxic activity was determined against MRC-5 cells to a...