background: colorectal cancer is one of the most common cancers and second leading cause of cancer deaths worldwide. every year nearly one million new cases of colorectal cancer are recognized around the world and nearly half of them lose their lives due to the disease. researches shown that in early diagnosis of this cancer 90% of patients can be treated. the fecal occult blood test (fobt) bec...

BACKGROUND Colorectal cancer screening and treatment are rapidly evolving. Aims To reappraise stool-based colorectal cancer screening in light of changing test performance characteristics, lower test cost and increasing colorectal cancer care costs. METHODS Using a Markov model, we compared faecal DNA testing every 3 years, annual faecal occult blood testing or immunochemical testing, and col...

BACKGROUND AND AIMS To determine the cost-effectiveness of screening for colorectal cancer using flexible sigmoidoscopy once every 10 years, compared with annual and biennial rehydrated Hemoccult fecal occult blood testing and colonoscopy once every 10 years, or no screening. METHODS A Markov model was developed in order to simulate the progression of a cohort of asymptomatic, average-risk in...

BACKGROUND Fecal occult blood testing, flexible sigmoidoscopy, and colonoscopy are used to screen patients for colorectal cancer. OBJECTIVE To compare the cost-effectiveness of fecal occult blood testing, flexible sigmoidoscopy, and colonoscopy. DESIGN The cost-effectiveness of the three screening strategies was compared by using computer models of a Markov process. In the model, a hypothet...