In this paper we generalize the framework of the feasible descent method (FDM) to a randomized (R-FDM) and a coordinate-wise random feasible descent method (RC-FDM) framework. We show that the famous SDCA algorithm for optimizing the SVM dual problem, or the stochastic coordinate descent method for the LASSO problem, fits into the framework of RC-FDM. We prove linear convergence for both R-FDM ...

In this paper we generalize the framework of the Feasible Descent Method (FDM) to a Randomized (R-FDM) and a Randomized Coordinate-wise Feasible Descent Method (RCFDM) framework. We show that many machine learning algorithms, including the famous SDCA algorithm for optimizing the SVM dual problem, or the stochastic coordinate descent method for the LASSO problem, fits into the framework of RC-F...

The prototype ferredoxin maquette, FdM, is a 16-amino acid peptide which efficiently incorporates a single [4Fe-4S]2+/+ cluster with spectroscopic and electrochemical properties that are typical of natural bacterial ferredoxins. Using this synthetic protein scaffold, we have investigated the role of the nonliganding amino acids in the assembly of the iron-sulfur cluster. In a stepwise fashion, ...

BACKGROUND The functional diffusion map (fDM) has been suggested as a tool for early detection of tumor treatment efficacy. We aim to study 3 factors that could act as potential confounders in the fDM: areas of necrosis, tumor grade, and change in tumor size. METHODS Thirty-four pediatric patients with brain tumors were enrolled in a retrospective study, approved by the local ethics committee...

Numerous studies suggest that dysfunctional basal ganglia-thalamo-cortical circuits are involved in both movement disorders and psychiatric impairments. The current exploratory investigation explored possible psychological differences, firstly between 24 healthy musicians (HM) and 24 musicians diagnosed with focal dystonia (FDM) (Study I), and secondly among 35 FDM patients only (Study II). Res...

OBJECTIVES Financial decision-making (FDM) is crucial for independent living. Due to cognitive decline that accompanies normal aging, older adults might have difficulties in some aspects of FDM. However, an improved knowledge, personal experience and affective decision-making, which are also related to normal aging, may lead to a stable or even improved age-related performance in some other asp...

PURPOSE Scleral remodeling is an important mechanism underlying the development of myopia. Atropine, an antagonist of G protein-coupled muscarinic receptors, is currently used as an off-label treatment for myopia. Regulator of G-protein signaling 2 (RGS2) functions as an intracellular selective inhibitor of muscarinic receptors. In this study we measured scleral RGS2 expression and scleral remo...

Fixation density maps (FDM) created from eye tracking experiments are widely used in image processing applications. The FDM are assumed to be reliable ground truths of human visual attention and as such one expects high similarity between FDM created in different laboratories. So far, no studies have analysed the degree of similarity between FDM from independent laboratories and the related imp...

Fabrication of Functionally Graded Parts Longmei Li, Q. Sun, C. Bellehumeur , and P. Gu 2 Department of Mechanical and Manufacturing Engineering Department of Chemical and Petroleum Engineering The University of Calgary, Calgary, Alberta, T2N 1N4, CANADA Abstract Solid Freeform Fabrication technologies have potential to manufacture parts with locally controlled properties (LCP), which would all...

The objective of this work can be divided into two parts. The first one is to propose an extension of the force density method (FDM)[2], a form-finding method for prestressed cable-net structures. The second one is to present a review of various formfinding methods for tension structures, in the relation with the extended FDM. In the first part, it is pointed out that the original FDM become us...