conclusions elevation of liver enzymes appears in 29 % obese children in a tertiary care centre. absolute alanine aminotransferase levels are significantly higher in obese than in overweight children. even obese children with normal liver enzymes show signs of fatty liver disease as demonstrated by liver enzymes at the upper limit of normal. results elevated alanine aminotransferase was observe...

context non-alcoholic fatty liver disease (nafld) is a chronic liver disease, with 5-10% of liver having extra fat. increase in its prevalence in all age groups is linked with obesity and type ii diabetes. the treatment of nafld remains controversial. a growing body of evidence suggests a relation between overgrowth of gut microbiota with nafld and non-alcoholic steatohepatitis (nash). the obje...

Background: Metabolic syndrome (MS) and non-alcoholic fatty liver disease (NAFLD) is a common public health problem. Visfatin is secreted by visceral adipose tissue and is an adipocytokine. It could be a pro-inflammatory adipocytokine and is related to the metabolic syndrome and non-alcoholic fatty liver disease. This study evaluated the association between visfatin levels in patients w...

Background: Non-alcoholic fatty liver disease (NAFLD) is increasingly a common disease which is created by the accumulation of fat in the liver. About 20% of adults and 5% of children suffer from this disease. In some studies, half of obese children had fatty liver disease and approximately 90% of the patients with fatty liver were obese. The aim of this study was to evaluate fatty liver diseas...

patients and methods eighty-three patients with diagnosis of nafld, and 93 healthy subjects were included in the study. tetra arms-pcr was designed to detect single nucleotide polymorphisms. results a significant difference was found between nafld and control group regarding the rs266729 polymorphism (χ2 = 7.35, p = 0.025). the rs266729 polymorphism increased the risk of nafld in codominant (cc...

background: non-alcoholic fatty liver disease (nafld) is characterized by fatty change of liver without inflammation. the aim of this study was to evaluate presence of clinical and metabolic components in non-diabetic patients with nafld and to assess the relationship between insulin resistance and these factors. materials andmethods: in this study, a group of 50 sonographically confirmed patie...