conclusions the current study adds evidence to the association of tnf-α gene polymorphism and ms in this southern south iranian population which is consistent with the genetic analysis of ms in europeans (games) project reports and these two alleles reported in this study may be one of the genetic risk factor for ms. furthermore, this data can be used to build the iranian gene bank for future s...

background tnf-α is one of the most potent cytokines in proinflammatory reactions. results one hundred and twenty children with acute pyelonephritis were evaluated. urinary tnf-α/cr was 0.0051 ± 0.00083 pg/g creatinine. the authors found out a significant difference in urinary tnf-α/cr between patients who have normal and abnormal levels of urine leukocytes, urine protein, urine culture, erythr...

results there was no difference found between the two groups with regard to; gender, basic variables, ejection fraction (ef), cbp time and aortic cross-clamp time. the preoperative levels of il-6 and tnf-α were not different; however, their postoperative levels were significantly higher in the placebo group (p value = 0.01 for il-6 and 0.005 for tnf-α). conclusions this study showed that mgso4 ...

conclusions taken together, pomegranate juice did not affect serum cytokines levels in patients with oa. its role in improving physical function in these patients most likely involves other mechanisms. background osteoarthritis (oa) is the most common musculoskeletal disorder causing disability and loss of function, particularly in the elderly. preclinical and in-vitro studies for mitigation of...

many species of tea (camellia sinensis) and cowslip (echium amoenum) are used in iranian traditional medicine. the aim of this study was to conduct the survey on the ability of iranian black tea and cowslip extracts on secretion of tumor necrosis factor-alpha (tnf-alpha) by non-infected and infected mouse macrophages. a macrophage infection model with legionella pneumophila and enzyme linked im...

conclusion: in this study group, tnf-α -238 polymorphism was shown to be different in preeclamptic and non-preeclamptic pregnant women. the aa genotype and the a allele may carry an increased risk for developing of preeclampsia. results: there were significant differences between the two groups in tnf-α genotype at position -238 (p < 0.001). in the preeclamptic group, the frequency of the aa ge...

background: despite the emerging evidence on beneficial effects of probiotics on the cardiovascular system, their impact on the management of ischemic heart diseases and its possible mechanism have not been elucidated. methods: four viable probiotics bacterial strains, including bifidobacterium breve, lactobacillus casei, lactobacillus bulgaricus and lactobacillus acidophilus, at the concentrat...

background:  levels of anti-inflammatory cytokines in blood have a positive relationship with congenital heart disease (chd). we sought to assess the difference in serum cytokines levels between children with and without chd.  methods:  we recruited 60 patients with chd and 30 healthy children, from 2013 to 2014. patients with primary pulmonary hypertension; metabolic diseases; renal, endocrine...