background: in recent years, various noninvasive respiratory support (nrs) of ventilation has been provided more in neonates. the aim of this study was to compare the effect of hfnc with ncpap in post-extubation of preterm infants with rds after insure method (intubation, surfactant, extubation). methods: a total of 54 preterm infants with rds (respiratory distress syndrome) were enrolled in th...

Background: In recent years, various noninvasive respiratory support (NRS) of ventilation has been provided more in neonates. The aim of this study was to compare the effect of HFNC with NCPAP in post-extubation of preterm infants with RDS after INSURE method (intubation, surfactant, extubation).Methods: A total of 54 preterm infants with RDS (respiratory distress syndrome) were enrolled in thi...

Purpose: To compare respiratory and clinical outcomes between the currently used strategy of Intubation, Surfactant, Extubation (InSurE) and nasal continuous positive airway pressure (NCPAP) and the alternative strategy of InSurE and nasal intermittent positive pressure ventilation (NIPPV) for the initial treatment of respiratory distress syndrome (RDS) in preterm newborns ≤32 weeks. Methods: T...

BACKGROUND Neonatal intubation is a stressful procedure that requires premedication to improve intubation conditions and reduce stress and adverse physiological responses. Premedication used during the INSURE (INtubation, SURfactant therapy, Extubation) procedure should have a very short duration of action with restoration of spontaneous breathing within a few minutes. AIMS To determine the b...

background:respiratory distress syndrome is the most common respiratory disease in premature neonate and the most important cause of death among them. we aimed to investigate factors to predict successful or failure of insure method as a therapeutic method of rds.methods:in a cohort study,45 neonates with diagnosed rds and birth weight lower than 1500g were included and they underwent insure fo...

BACKGROUND In recent years, various noninvasive respiratory support (NRS) of ventilation has been provided more in neonates. The aim of this study was to compare the effect of HFNC with NCPAP in post-extubation of preterm infants with RDS after INSURE method (intubation, surfactant, extubation). METHODS A total of 54 preterm infants with RDS (respiratory distress syndrome) were enrolled in th...

Objective : To identify which factors can predict INSURE failure in preterm infants with respiratory distress syndrome. Study design : A retropective analysis of the prenatal histories, clinical courses and paraclinical data of all inborn infants (birth weight < 2000g) with respiratory distress syndrome treated with INSURE method. Infants were categorized into 2 groups : "INSURE failure group" ...

Background: The cornerstone of the treatment of respiratory distress syndrome (RDS) is respiratory support and surfactant replacement therapy. The administration of surfactant through a thin intratracheal catheter is one of the methods used to reduce one of the standard technique complications of a surfactant injection (Intubation-Surfactant-Extubation method [INSURE]). The aim of this study wa...

BACKGROUND The INtubation-SURfactant-Extubation (INSURE) is a procedure that is increasingly being used to treat the respiratory distress syndrome in preterm infants. The objective of this study was to identify predictors for an unsuccessful INSURE procedure. METHODS The neonates included were less than 32 weeks' gestation, treated with surfactant in the neonatal intensive care unit, and born...

administration of endotracheal surfactant is potentially the main treatment for neonates suffering from rds (respiratory distress syndrome), which is followed by mechanical ventilation. late and severe complications may develop as a consequence of using mechanical ventilation. in this study, conventional methods for treatment of rds are compared with surfactant administration, use of mechanical...