introduction  mechanical ventilation may be lifesaving intervention,it can be associated with complications,thus,successful weaning is constitutive.one of the factors which is  important in successful weaning is  method of weaning. it is shown that  weaning is conducted successfully by using spontaneous breathing trial (sbt) through t-piece and pressure support (ps) ventilation.but few studies ...

objective neuromuscular disorders (diseases of the motor unit), can cause respiratory problems such as impaired cough reflex, chest deformity, recurrent pneumonia and acute respiratory failure; these are the worst most common complications of these diseases and the leading cause of death in such patients (1, 2). their management hence, very often, entails admission to the pediatric intensive ca...

BACKGROUND The ideal timing for extubation of patients with myasthenic crisis (MC) and the factors that influence extubation outcome are not well established. OBJECTIVES To assess the risk of extubation failure in MC and to identify predictors of extubation failure. DESIGN We reviewed consecutive episodes of MC treated with endotracheal intubation from January 1, 1987, through December 31, ...

OBJECTIVE To evaluate the association between extubation failure and outcomes (clinical and functional) in patients with traumatic brain injury (TBI). METHODS A prospective cohort study involving 311 consecutive patients with TBI. The patients were divided into two groups according to extubation outcome: extubation success; and extubation failure (defined as reintubation within 48 h after ext...

Background:  Successful weaning of the ventilator is a major challenge, especially in children. This study was conducted to compare the criteria of readiness for extubation and daily spontaneous breathing test (SBT) on the duration of mechanical ventilation and extubation failure rates. Materials and Metho...

conclusions although some studies showed association between anemia and extubation failure, the current study could not confirm it. the study showed that males, regardless of the hct level, had a better extubation success rate than those of females. results there was no significant association between the level of hct concentration and extubation failure (8.9% vs. 9.2%, p = 0.507). gender and a...

Extubation failure, or the need for reintubation within 24–72 hours of extubation, occurs in up to 25% of critically ill patients. Extubation failure is associated with a markedly increased morbidity and mortality, including duration of mechanical ventilation, intensive care unit (ICU) and hospital stay, the need for post-acute-care hospitalization, and the need for tracheostomy.1,2 The most co...

BACKGROUND The effectiveness of noninvasive ventilation (NIV) after extubation in preventing post-extubation respiratory failure is still controversial. METHODS We conducted a prospective, multicenter randomized controlled study involving patients on mechanical ventilation for > 48 hours who tolerated a 2-hour spontaneous breathing trial and were subsequently extubated. The patients were ran...

BACKGROUND Extubation failure is defined as the re-institution of respiratory support ranging from 24 to 72 hours following scheduled extubation and occurs in 2% to 25% of extubated patients. The aim of this study was to determine clinical and surgical risk factors that may predict extubation failure in patients submitted to non-emergency intracranial surgery. METHODS This was a prospective o...