in recent years the science of tissue engineering has emerged as a powerful tool for the development of a novel set of tissue replacement parts and technologies. recent advances in the fields of biomaterials, stem cell technologies, growth factor field and biomimetics have created a unique set of opportunities for investigators to fabricate lab-grown tissues from combination of extracellular ma...

The extracellular matrix of cartilage and bone is composed mostly of collagen with lesser amounts of other constituents such as proteoglycans. The focus of this brief review will be on the dynamic expression of collagens and proteoglycans in the cartilage and bone extracellular matrices. Recent research has shown the presence of different collagen types and proteoglycans that are differentially...