Introduction: The basolateral amygdala (BLA) and infralimbic area (IL) of the medial prefrontal cortex (mPFC) are two interconnected brain structures that mediate both fear memory expression and extinction. Besides the well-known role of the BLA in the acquisition and expression of fear memory, projections from IL to BLA inhibit fear expression and have a critical role in fear extinction. Howev...

introduction: one of the hallmark symptoms of posttraumatic stress disorder (ptsd) is the impaired extinction of traumatic memory. single prolonged stress (sps) has been suggested as an animal model of ptsd, since sps rats exhibited the impaired fear extinction. oxytocin (oxt) has been recently suggested as a potential pharmacotherapy for treatment of ptsd. in this study, using sps rats we inve...

Introduction: One of the hallmark symptoms of posttraumatic stress disorder (PTSD) is the impaired extinction of traumatic memory. Single prolonged stress (SPS) has been suggested as an animal model of PTSD, since SPS rats exhibited the impaired fear extinction. Oxytocin (OXT) has been recently suggested as a potential pharmacotherapy for treatment of PTSD. In this study, using SPS rats we inve...

Introduction: This study investigates the effects of cannabinoid agonist WIN55-212-2 on acquisition and consolidation phases of the fear memory extinction and also on anxiety and motor activity. Methods: In this study, we used SPS & S model to induce post-traumatic stress disorder. One week after SPS, to establish a conditioned fear memory, rats received an electric foot shock within shock cha...

Around 75% of civilians have experienced at least one traumatic event in their lives, and this number is considerably higher in many parts of the world, as well as in military veterans and first responders. Of those exposed to trauma, 15-25% will develop Posttraumatic Stress Disorder (PTSD).  PTSD extracts enormous economic, health, and quality of life cost. Thus, it is critical to underst...

a detailed study of ostracoda changes against the stable isotopes of carbon and oxygen acrossthe cenomanian-turonian boundary mass extinction has been fully documented in one section, the south ofengland. this section comprises the uppermost cenomanian to lowermost turonian strata. the comparisonbetween the results obtained in this research and two rival models for the cenomanian-turonian bound...

About 35 samples were collected from lower and upper parts of the proposed Frasnianamennian boundary in three sections of Upper Devonian marine sediments of the Kerman province. The biostratigraphical and geochemical studies indicate that about 45% extinction of brachiopods probably caused by the Frasnian-Famennian bioevents, which is slightly higher than thr rate of Devonian-Carboniferous exti...

about 35 samples were collected from lower and upper parts of the proposed frasnianamennian boundary in three sections of upper devonian marine sediments of the kerman province. the biostratigraphical and geochemical studies indicate that about 45% extinction of brachiopods probably caused by the frasnian-famennian bioevents, which is slightly higher than thr rate of devonian-carboniferous exti...

atmospheric visibility is a key factor in everyday life mainly in aviation, industry and surface traffic. it has been defined as the greatest distance at which an observer can just see a black object viewed against the horizon sky which is known as the visual range. furthermore, light extinction which is mostly due to absorption and scattering effects of aerosols in the atmosphere, can be calcu...