نتایج جستجو برای: external validation gc gc

تعداد نتایج: 393236  

Journal: :journal of chemical health risks 0
majid mohammadhosseini

a reliable quantitative structure retention relationship (qsrr) study has been evaluated to predict the retention indices (ris) of a broad spectrum of compounds, namely 118 non-linear, cyclic and heterocyclic terpenoids (both saturated and unsaturated), on an hp-5ms fused silica column. a principal component analysis showed that seven compounds lay outside of the main cluster. after elimination...

Journal: :American journal of epidemiology 2012
Jennifer S Sonderman Heather M Munro William J Blot Lisa B Signorello

Prospective epidemiologic studies generally rely on 1 baseline biologic sample from participants for measurement of prediagnostic biomarkers, assuming that 1 measurement adequately represents the participant's "typical" level. The body of work assessing the reproducibility of circulating serum 25-hydroxyvitamin D (25(OH)D) levels over time focuses almost exclusively on populations of European d...

2014
Anirban P. Mitra Lucia L. Lam Mercedeh Ghadessi Nicholas Erho Ismael A. Vergara Mohammed Alshalalfa Christine Buerki Zaid Haddad Thomas Sierocinski Timothy J. Triche Eila C. Skinner Elai Davicioni Siamak Daneshmand Peter C. Black

BACKGROUND Nearly half of muscle-invasive bladder cancer patients succumb to their disease following cystectomy. Selecting candidates for adjuvant therapy is currently based on clinical parameters with limited predictive power. This study aimed to develop and validate genomic-based signatures that can better identify patients at risk for recurrence than clinical models alone. METHODS Transcri...

2013
Hadi Noorizadeh Hamid Karimi Abbas Farmany

Genetic algorithm and partial least square (GA-PLS) technique was used to investigate the correlation between linear retention index (LRI) for Teucrium chamaedrys volatiles which were obtained by direct thermal desorption (DTD) technique with comprehensive two-dimensional (2D) gas chromatography-time-of-flight mass spectrometry (GC×GC-TOF/MS). The applied internal (leave-group-out cross validat...

2015
Xin Zhou Wei Zhu Hai Li Wei Wen Wenfang Cheng Fang Wang Yinxia Wu Lianwen Qi Yong Fan Yan Chen Yin Ding Jing Xu Jiaqi Qian Zebo Huang Tongshan Wang Danxia Zhu Yongqian Shu Ping Liu

The differential expression of microRNAs (miRNAs) in plasma of gastric cancer (GC) patients may serve as a diagnostic biomarker. A total of 33 miRNAs were identified through the initial screening phase (3 GC pools vs. 1 normal control (NC) pool) using quantitative reverse transcription polymerase chain reaction (qRT-PCR) based Exiqon panel (miRCURY-Ready-to-Use-PCR-Human-panel-I + II-V1.M). By ...

2017
Skye Hung-Chun Cheng Tzu-Ting Huang Yu-Hao Cheng Tee Benita Kiat Tan Chen-Fang Horng Yong Alison Wang Nicholas Shannon Brian Li-Sun Shih Ben-Long Yu

We validated an 18-gene classifier (GC) initially developed to predict local/regional recurrence after mastectomy in estimating distant metastasis risk. The 18-gene scoring algorithm defines scores as: <21, low risk; ≥21, high risk. Six hundred eighty-three patients with primary operable breast cancer and fresh frozen tumor tissues available were included. The primary outcome was the 5-year pro...

Journal: :Gut 2013
Yonghui Wu Heike Grabsch Tatiana Ivanova Iain Beehuat Tan Jacinta Murray Chia Huey Ooi Alexander Ian Wright Nicholas P West Gordon G A Hutchins Jeanie Wu Minghui Lee Julian Lee Jun Hao Koo Khay Guan Yeoh Nicole van Grieken Bauke Ylstra Sun Young Rha Jaffer A Ajani Jae Ho Cheong Sung Hoon Noh Kiat Hon Lim Alex Boussioutas Ju-Seog Lee Patrick Tan

OBJECTIVE Gastric adenocarcinoma (gastric cancer, GC) is a major cause of global cancer mortality. Identifying molecular programmes contributing to GC patient survival may improve our understanding of GC pathogenesis, highlight new prognostic factors and reveal novel therapeutic targets. The authors aimed to produce a comprehensive inventory of gene expression programmes expressed in primary GC...

2018
Jing Guo Shangxiang Chen Shun Li Xiaowei Sun Wei Li Zhiwei Zhou Yingbo Chen Dazhi Xu

Several studies have highlighted the prognostic value of the individual and the various combinations of the tumor markers for gastric cancer (GC). Our study was designed to assess establish a new novel model incorporating carcino-embryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), carbohydrate antigen 72-4 (CA72-4). A total of 1,566 GC patients (Primary cohort) between Jan 2000 and Jul...

Journal: :Arthritis research & therapy 2016
Tamarah D de Jong Saskia Vosslamber Elise Mantel Sander de Ridder John G Wesseling Tineke C T M van der Pouw Kraan Cyra Leurs Harald Hegen Florian Deisenhammer Joep Killestein Ingrid E Lundberg Jiri Vencovsky Mike T Nurmohamed Dirkjan van Schaardenburg Irene E M Bultink Alexandre E Voskuyl D Michiel Pegtel Conny J van der Laken Johannes W J Bijlsma Cornelis L Verweij

BACKGROUND Activation of the type I interferon (IFN) response program is described for several autoimmune diseases, including systemic lupus erythematosus (SLE), multiple sclerosis (MS), myositis (IIM) and rheumatoid arthritis (RA). While IFNα contributes to SLE pathology, IFNβ therapy is often beneficial in MS, implying different immunoregulatory roles for these IFNs. This study was aimed to i...

2013
Paul A Ginno Yoong Wearn Lim Paul L Lott Paul A. Ginno Paul L. Lott Ian Korf Frédéric Chédin

P<P Published online July 18, 2013 in advance of the print journal. Preprint Accepted likely to differ from the final, published version. Peer-reviewed and accepted for publication but not copyedited or typeset; preprint is License Commons Creative . http://creativecommons.org/licenses/by-nc/3.0/ described at a Creative Commons License (Attribution-NonCommercial 3.0 Unported), as ). After six m...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید