background escherichia coli (e. coli) species are able to produce extended-spectrum β-lactamases (esbls) that cause high resistance to the beta-lactam antibiotics. therefore, determining the antibiotic susceptibility patterns in resistant organisms is necessary for suitable therapeutic approaches. patients and methods totally, 260 clinical isolates of e. coli were collected from hospitals in te...

background & objectives:extended-spectrum-b-lactamase (esbl)-producing strains of klebsiella pneumoniaare an important cause of many serious infections in hospitalized and nonhospitalized patients and delayed treatment of these infections in crease chance of death in patients. this study was performed to determine the prevalence of esbl-producing k. pneumonia and to evaluate the frequency o...

conclusions according to our results, blatem-116 was the most frequent isolated esbl gene among the p. aeruginosa strains isolated from patients. results ciprofloxacin and piperacillin were the most efficient antipseudomonal agents. the results disclosed that 19 (16.37%) of the isolates were multidrug resistant and 8 (6.89%) were esbl-positive. of the 116 isolates, 30 (25.86%) were resistant to...

background clinical significance of extended-spectrum beta-lactamases (esbls) production in enterobacter spp. has not well been established. objectives this study was conducted to investigate the prevalence of esbls produced by enterobacter spp. in clinical isolates. materials and methods this descriptive cross-sectional study was performed during may 2010 to april 2012 in the city of sanandaj,...

introduction: extended spectrum beta-lactamase (esbl) producing escherichia coli generate a major problem for clinical therapeutics and epidemiological study. the incidence of esbl producing strains among clinical isolates has been steadily increasing during the past few years, and remains an important cause of failure of therapy with cephalosporins. the aim of this study was to determine the a...

background and objectives: klebsiella pneumoniae is an opportunistic pathogen responsible for up to 10% of nosocomial infections. the emergence and spread of multidrug resistant k. pneumoniae , mostly due to the production of extended-spec- trum β-lactamases (esbl) and carbapenemases, is often responsible for antibiotic treatment failure of these infections. we compared the antibiotic resistanc...

background and objective: nowadays, the presence of extended-spectrum β-lactamases (esbls) producing strains in serratia genus causes the emergence of resistance to many antibiotics. so, the lack of proper diagnosis of esbls strains can lead to failure in the treatment. the objective of the present study was to investigate esbls production in serratia strains isolated from the clinical blood sa...

objective(s): drug resistant acinetobacter baumannii have emerged as a major problem in many hospitals and intensive care units. various types of extended spectrum beta-lactamases (esbls) are responsible for resistance to beta- lactam antibiotics in different parts of the world. the objective of this study was to determine the prevalence of integron class1 (int 1) and esbl types per-1, per-2 an...

conclusions the results of this study phenotypically and genotypically confirmed the high frequency of esbl-producing strains, such as the ctx-m and ctx-m-1 genes, among enterobacteriaceae isolates in our region. therefore, use of antibiotic susceptibility testing for the detection of esbl isolates prior to the prescription of beta-lactam antibiotics is recommended. this could help prevent the ...

conclusions this study was the first report of the emergence of the plasmid-encoded blaoxa genes among e. cloacae isolates in iran. these findings highlight the need to use appropriate infection control policy and rational antibiotic therapy to reduce further spread of these resistant bacteria in the studied hospitals. results in total, 48 esbl-producing isolates (58.5%) were positive for the b...