نتایج جستجو برای: expression of core gene

تعداد نتایج: 21310892  

Journal: :modares journal of medical sciences: pathobiology 2006
nasrin rastgoo ali karami farzaneh sabahi

introduction: hepatitis c virus (hcv) is the major cause of acute and chronic hepatitis, cirrhosis, and hepatocellular carcinoma worldwide. because of increasing number of infected patients throughout the world, various studies are concentrated on development of high quality diagnostic tests and genotyping in various regions of the world. methods: in this study, we used rt-pcr to isolate and a...

Abstract_ Introduction: Viola plant has been used traditionally for the treatment of neurological disorders. We aimed at determining whether pretreatment with Viola spathulata extract can alleviate the severity of ischemic-reperfusion damages and it can exert its protective effects through the regulation of a sodium/calcium exchanger (NCX3) gene expression in a rat brain. Methods: Male Wistar r...

F Sabahi , M Ravanshad , M Saberi-Firoozi , MH Modarressi , SM Moazzeni , SY Hosseini ,

Background and Aims: DNA constructs containing HCV antigens have become one of the vaccine candidates for induction of anti-HCV cellular and humoral immunity. In this study, we constructed a novel expressing vector harboring a fusion sequence derived from an overlapping fragment in the middle of NS3 and a truncated core fragment to avoid troubles reported to be associated with full gene express...

Bayat H Ohadi M Valipour E,

Background: We examine the GA-repeat core promoters of MECOM and GABRA3 in human embryonic kidney-293 cell line and show that those GA-repeats have promoter activity,and those different alleles of the repeats can significantly alter gene expression.We propose a novel role for GA-repeat core promoters to regulate gene expression in the genes involved in development and evolution. Materials and M...

Alexis Musacchio, Mohammad Azizi, Nelvis Figueroa, Ornaldo Pardo, Verena Muzio,

DNA coding for the core antigen from hepatitis B Virus (HBcAg) was amplified, cloned and propagated in E. coli. The core protein was expressed in E. coli and the product was readily detected by Western blot. This protein can be used as a diagnostic material in serum screening tests. To increase the level of expression of this antigen in bacteria, two plasmids were constructed in which the gene ...

ژورنال: یافته 2016

Background : Hepatitis C virus (HCV) is considered as one of the major pathogenic agents of chronic liver diseases. Previous studies have shown that HCV proteins can interaction with gene regulatory networks such as microRNAs. The aim of this study was to investigate the effect of HCV core protein on the expression of miR-150 in a cell culture model. Materials and Methods: Plasmids expressin...

پایان نامه :دانشگاه تربیت معلم - تهران - دانشکده زیست شناسی 1391

بررسی تآثیر کورکومین بر بیان آکواپورین5 در سلول های سرطانی روده بزرگ انسان(ht-29) سرطان روده بزرگ جزو بیماری های خطرناک بوده و از نظر شیوع سومین سرطان شایع و دومین علت مرگ ومیر ناشی از سرطان در جهان محسوب می شود. خطرابتلا به این سرطان تحت تاثیر دو عامل محیطی وفاکتورهای ژنتیکی می باشد. آکواپورین ها، پروتئین های کانال آبی بوده که نقش مهمی را در انتقال آب در بافتهای اندوتلیالی و اپی تلیالی بر عهد...

Journal: :iranian journal of virology 0
sy hosseini department of virology, tarbiat modares university, tehran, iran f sabahi department of virology, tarbiat modares university, tehran, iran sm moazzeni department of immunology, tarbiat modares university, tehran, iran mh modarressi department of medical genetic, tehran university of medical sciences, tehran, irandepartment of medical genetic, tehran university of medical sciences, tehran, iran m saberi-firoozi gastroenterohepatology research center, shiraz university of medical sciences, shiraz, iran m ravanshad department of virology, tarbiat modares university, tehran, iran

background and aims: dna constructs containing hcv antigens have become one of the vaccine candidates for induction of anti-hcv cellular and humoral immunity. in this study, we constructed a novel expressing vector harboring a fusion sequence derived from an overlapping fragment in the middle of ns3 and a truncated core fragment to avoid troubles reported to be associated with full gene express...

Journal: :iranian biomedical journal 0
محمد عزیزی mohammad azizi alexis musacchio ornaldo pardo nelvis figueroa verena muzio

dna coding for the core antigen from hepatitis b virus (hbcag) was amplified, cloned and propagated in e. coli. the core protein was expressed in e. coli and the product was readily detected by western blot. this protein can be used as a diagnostic material in serum screening tests. to increase the level of expression of this antigen in bacteria, two plasmids were constructed in which the gene ...

Journal: :hepatitis monthly 0
seyed younes hosseini department of virology, vaswmu} oodmwe{cuniwg{wow}s, tarbiat modares university, p. o. box: 14115-331, ir iran +98-2182883880, [email protected]; gastroentero -hepatology research center, shiraz university of medical sciences, ir iran farzaneh sabahi department of virology, vaswmu} oodmwe{cuniwg{wow}s, tarbiat modares university, p. o. box: 14115-331, ir iran +98-2182883880, [email protected]; department of virology, vaswmu} oodmwe{cuniwg{wow}s, tarbiat modares university, p. o. box: 14115-331, ir iran +98-2182883880, [email protected] seyed mohammad moazzeni department of immunology, tarbiat modares university, ir iran mohammad hossein modarressi department of medical genetic, tehran university of medical sciences, ir iran mehdi saberi firoozi digestive disease research center, tehran university of medical sciences, ir iran mehrdad ravanshad department of virology, vaswmu} oodmwe{cuniwg{wow}s, tarbiat modares university, p. o. box: 14115-331, ir iran +98-2182883880, [email protected]

background in spite of dozens of clinical trials to establish effective therapeutic and/or preventive vaccine to resolve hcv infection, no real vaccine has been proved to date. genetic vaccines based on replication-defective adenoviruses have proved to elicit strong and long lasting t-cell responses against a number of viral antigens and are even currently being used for vaccine trials in human...

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