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Individual differences in the temporal dynamics of the haemodynamic response can reflect cortical excitation and can reveal underlying cortical physiology. Here, we show differences in the shape of the haemodynamic response that are dependent on stimulus parameters. Two sets of visual stimuli were used varying in parameters that are known to manipulate the haemodynamic response in the visual co...

introduction: anodal transcranial direct current stimulation (a-tdcs) of the primary motor cortex (m1) has been shown to be effective in increasing corticomotor excitability. 　methods: we investigated whether longer applications of a-tdcs coincide with greater increases in corticomotor excitability compared to shorter application of a-tdcs. ten right-handed healthy participants received one ses...

the purpose of the this study was to investigate the effect of direct current on montoneuron reflex exitability. thirty six subjects (18 males, 18 females) 19.36 years of age ( x= 24.06, sd= 3.63) participated in this study. the reflex excitability of soleus motoneruons was assessed by measuring the amount of change in the peak to peak ampitude of the h-reflex before and after direct current wa...

introduction: anethole is the main constituent of pimpinella anisum l. (anise), a herbaceous annual plant which has several therapeutic effects. in the folk medicine, anise is employed as an antiepileptic drug. specifically, this study was focused on the cellular effect of anethole, an aromatic compound in essential oils from anise and camphor. anethole has various physiological effects on the ...

Stimulation at specific acupoints can activate cortical regions in human subjects. Previous studies have mainly focused on a single brain region. However, the brain is a network and many brain regions participate in the same task. The study of a single brain region alone cannot clearly explain any brain-related issues. Therefore, for the present study, magnetic stimulation was used to stimulate...

introduction: the functional effects of orexin-b on the calcium spikes and excitability of the neuronal soma membrane of garden snail, helix aspersa were studied. methods: conventional intracellular recording, under the current clamp conditions was performed to examine the effects of orexin-b on the configuration and electrophysiological properties of calcium spikes. results: application of ore...

The dentate gyrus is the main entrance of highly processed information to the hippocampus which derives from associative cortices and it is one of the few privileged areas in the brain where adult neurogenesis occurs. This creates the unique situation that neurons of diverse maturation stages are part of one neuronal network at any given point in life. While recently adult-born cells have a low...