نتایج جستجو برای: establishment

تعداد نتایج: 65220  

Journal: :The Journal of Cell Biology 2003
Meng-Fu Bryan Tsou Wei Ku Adam Hayashi Lesilee S. Rose

During intrinsically asymmetric division, the spindle is oriented onto a polarized axis specified by a group of conserved PAR proteins. Extrinsic geometric asymmetry generated by cell shape also affects spindle orientation in some systems, but how intrinsic and extrinsic mechanisms coexist without interfering with each other is unknown. In some asymmetrically dividing cells of the wild-type Cae...

Ali Ayoubian, Ehsan Teymourzadeh Gholam Hossein Alishiri Mohammadkarim Bahadori Seyed Mojtaba Hosseini

Background: It is important to set up hospitals, since they play a key role in providing health care services based on the budget allocated to the health sector. Objective:  This study evaluated factors militating against the establishment of hospitals in Iran. It also emphasized the importance of health care services. Methods: This...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد تهران مرکزی - دانشکده ادبیات و علوم انسانی 1391

peace and national security protection and ironic solving of international conflicts become the preliminary foundation of the united nations charter and had been considered as the main responsibilities of the security council, after world war ii and the establishment of united nations organization. therefore, the security council enables to analyze every kind of conflicts and challenges which ...

2014
Yuan Zhong Shijie He Chunying Dong Baohua Ji Gengkai Hu

Article history: Received 26 August 2013 Accepted 11 November 2013 Available online 24 April 2014

2017
Lindsey Seldin Ian Macara

Mitotic spindle orientation is a conserved, dynamic, and highly complex process that plays a key role in dictating the cleavage plane, fate, and positioning of cells within a tissue, therefore laying the blueprint for tissue structure and function. While the spindle-positioning pathway has been extensively studied in lower-model organisms, research over the past several years has highlighted it...

Journal: :hospital practice and research 0
mohammadkarim bahadori health management research center, baqiyatallah university of medical sciences, tehran, iran ehsan teymourzadeh health management research center, baqiyatallah university of medical sciences, tehran, iran seyed mojtaba hosseini department of health services management, tehran north branch, islamic azad university, tehran, iran gholam hossein alishiri department of clinical research, baqiyatallah hospital, tehran, iran ali ayoubian department of health services management, tehran north branch, islamic azad university, tehran, iran

background: it is important to set up hospitals, since they play a key role in providing health care services based on the budget allocated to the health sector. objective:  this study evaluated factors militating against the establishment of hospitals in iran. it also emphasized the importance of health care services. methods: this cross-sectional study was conducted in 2012 using a qualitativ...

2013
Laurin Lengert Barbara Drossel

By using fluorescent labelling techniques, the distribution and dynamics of proteins can be measured within living cells, allowing to study in vivo the response of cells to a triggering event, such as DNA damage. In order to evaluate the reaction rate constants and to identify the proteins and reactions that are essential for the investigated process, mechanistic models are used, which often co...

Journal: :Current Biology 2004
J. Wandelt L. M. Nagy

Snail shells can be left-handed or right-handed, sometimes within one species. For over a century, it has commonly been assumed that mirror-image shell coiling in snails is correlated with a mirror- image reversal of early spindle orientation and cleavage. The results of an exciting and elegant new study refute this model, showing that right doesn't have to be the mirror image of left.

Journal: :The Journal of Cell Biology 1992
U Euteneuer M Schliwa

Locomoting cells are characterized by a pronounced external and internal anterior-posterior polarity. One of the events associated with cell polarization at the onset of locomotion is a shift of the centrosome, or MTOC, ahead of the nucleus. This position is believed to be of strategic importance for directional cell movement and cell polarity. We have used BSC-1 cells at the edge of an in vitr...

Journal: :Methods in molecular biology 2014
Justin Decarreau Jonathan Driver Charles Asbury Linda Wordeman

Factors that influence the orientation of the mitotic spindle are important for the maintenance of stem cell populations and in cancer development. However, screening for these factors requires rapid quantification of alterations of the angle of the mitotic spindle in cultured cell lines. Here we describe a method to image mitotic cells and rapidly score the angle of the mitotic spindle using a...

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