The dynamical behaviour of the forced escape oscillator, which depends on the parameter values we considered, have been studied numerically using the techniques of phase portraits and Poincar'{e} sections. Also, we employed perturbation methods such as Lindstedt's method to obtain the frequency-amplitude relation of escape oscillator.

The escape from a metastable state over an oscillating barrier of an underdamped Josephson tunnel junction has been experimentally investigated with oscillation frequency well separated from the plasma frequency of the junction. The resonant escape, namely, a minimum of the average escape time as a function of the oscillation frequency, was observed. For the oscillation frequency much smaller t...

the dynamical behaviour of the forced escape oscillator, which depends on the parameter values we considered, have been studied numerically using the techniques of phase portraits and poincar'{e} sections. also, we employed perturbation methods such as lindstedt's method to obtain the frequency-amplitude relation of escape oscillator.

Noise-induced escape from a metastable state is studied for an overdamped periodically modulated system. We develop an asymptotic technique that gives both the instantaneous and period-average escape rates, including the prefactor, for an arbitrary modulation amplitude A . We find the parameter range where escape is strongly synchronized and the instantaneous escape rate displays sharp peaks. T...

Selection has been invaluable for genetic manipulation, although counter-selection has historically exhibited limited robustness and convenience. TolC, an outer membrane pore involved in transmembrane transport in E. coli, has been implemented as a selectable/counter-selectable marker, but counter-selection escape frequency using colicin E1 precludes using tolC for inefficient genetic manipulat...

Activated escape is investigated for systems that are driven by noise whose power spectrum peaks at a finite frequency. Analytic theory and analog and digital experiments show that the system dynamics during escape exhibit a symmetry-breaking transition as the width of the fluctuational spectral peak is varied. For double-well potentials, even a small asymmetry may result in a parametrically la...

S1 Fig-S4 Fig show the 5’, 3’, and full escape graphs for CH40, CH58, CH77 and CH256. Vertices are colored yellow and red to represent initial and expansion vertices. Uncolored vertices represent vertices we ignored in forming an escape tree as described in the Methods. The 5’ epitopes are underlined in the full escape graph. Above each vertex is the associated variant frequency at the first an...

SIV(mac239) infection of rhesus macaques (RMs) results in AIDS despite the generation of a strong antiviral cytotoxic T lymphocyte (CTL) response, possibly due to the emergence of viral escape mutants that prevent recognition of infected cells by CTLs. To determine the anatomic origin of these SIV mutants, we longitudinally assessed the presence of CTL escape variants in two MamuA*01-restricted...

Videotaped recordings of adult lobsters of different molt stages were analyzed. The escape response of adults was compared with that of juveniles recorded in an earlier study. Juvenile lobsters always respond to a threat with escape behavior irrespective of their molt stage, but in adults the probability of eliciting a response was a function of molt stage: more hard-shelled (intermolt stage C)...